Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Hainan Provincial Key Lab. of Fine Chem., Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou, 570228, China.
Org Biomol Chem. 2023 May 31;21(21):4398-4403. doi: 10.1039/d3ob00260h.
The C-H amination and C-O alkenylation of aryl triflates was achieved through Pd/norbornene (NBE) cooperative catalysis. By this strategy, various -alkenyl tertiary anilines including those bearing functional groups were produced in good to excellent yields. This reaction represents a new conversion model for phenoxides. It expands the scope of Catellani-type reactions and the application of phenoxides in organic synthesis.
芳基三氟甲磺酸酯的 C-H 胺化和 C-O 烯丙基化反应通过 Pd/降冰片烯（NBE）协同催化实现。通过该策略，可以高产率地制备各种 -烯基叔芳基苯胺，包括带有官能团的 -烯基叔芳基苯胺。该反应代表了酚氧化物的一种新的转化模式。它扩展了 Catellani 型反应的范围以及酚氧化物在有机合成中的应用。
