Eremina L A, Siniukov P A, Slonimskaia E M
Vopr Onkol. 1986;32(5):29-36.
The results of treatment of 134 cases of morphologically-verified localized Ewing's sarcoma were evaluated. A comparative analysis showed relapse-free survival to be significantly lower for radiation treatment (23%) than for its combination with various cytostatic drugs. Two-year relapse-free survival rate was as high as 43% in cases receiving sarcolysin or cyclophosphamide as adjuvants. This was matched by 47% for adjuvant adriamycin or carminomycin and 56% for adriamycin plus cyclophosphamide and vincristine. Evaluation of long-term results of adjuvant chemotherapy showed sex, age and site of involvement to be of certain prognostic value.
对134例经形态学证实的局限性尤因肉瘤的治疗结果进行了评估。比较分析显示,放射治疗的无复发生存率(23%)显著低于其与各种细胞毒性药物联合使用时的无复发生存率。在接受溶肉瘤素或环磷酰胺作为辅助药物的病例中,两年无复发生存率高达43%。辅助使用阿霉素或卡红菌素时,该比率为47%;辅助使用阿霉素加环磷酰胺和长春新碱时,该比率为56%。辅助化疗长期结果的评估显示,性别、年龄和受累部位具有一定的预后价值。