Department of Ophthalmology, East Tallinn Central Hospital, Tallinn, Estonia.
Department of Ophthalmology, Tartu University Hospital, Tartu, Estonia.
Klin Monbl Augenheilkd. 2023 Apr;240(4):569-573. doi: 10.1055/a-2013-2823. Epub 2023 Apr 25.
Retinal periphlebitis (RPP) is a long-known entity in patients with multiple sclerosis (MS) and has not been revisited in the context of recent developments in MS pathogenesis and heterogeneity. We present six cases of RPP in three female and three male MS patients. They all have relapsing-remitting MS and did not have or had minor ocular symptoms. It is important to perform a thorough retinal examination in patients with MS, as peripheral and sectorial lesions could be unseen. A better knowledge on the concomitant involvement of retinal veins contributes to the understanding of immunopathology, with potentially distinct autoantigenic targets. RPP might serve as a subphenotype marker that may influence treatment choices in MS. Further research is needed.
视网膜血管炎（RPP）是多发性硬化症（MS）患者中一种众所周知的疾病，在 MS 发病机制和异质性的最新研究中尚未被重新研究。我们报告了 6 例 MS 患者中的 3 例女性和 3 例男性的 RPP 病例。他们都患有复发缓解型多发性硬化症，且没有或仅有轻微的眼部症状。对 MS 患者进行彻底的视网膜检查非常重要，因为周边和扇形病变可能看不见。对视网膜静脉同时受累的更深入了解有助于理解免疫病理学，可能涉及不同的自身抗原靶点。RPP 可能作为一个亚表型标志物，可能影响 MS 的治疗选择。需要进一步的研究。
