Department of Epidemiology and Biostatistics, School of Public Health, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Department of Reproductive Health and Nutrition, School of Public Health, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
BMC Public Health. 2023 May 10;23(1):843. doi: 10.1186/s12889-023-15794-6.
Pregnancy-induced hypertension is the new onset of high blood pressure after 20 weeks of gestation in women with previously normal blood pressure. To the best of our knowledge, no study has been conducted in our country to investigate the association between this pregnancy problem and iron-folic acid supplementation. The aim of this study was to determine the association between iron-folic acid supplementation and pregnancy-induced hypertension (PIH) in pregnant women at public hospitals in the Wolaita Sodo zone.
An institution-based case-control study was conducted among pregnant women who visited public hospitals in the Wolaita Sodo zone from March 3, 2022, to August 30, 2022. A consecutive sampling method was used to select the study participants. The total sample size was 492, of which 164 were cases and 328 were controls. The data were collected by conducting face-to-face interviews and measurements. The data were entered into EpiData version 4.6 and exported to STATA 14 for analysis. Those variables with a p-value less than 0.05 were considered statistically significant. Descriptive statistics and odds ratios were presented using texts, tables, and figures.
A total of 471 women participated in this study, yielding a response rate of 96%. The cases had a mean age of 25 ± 4.43, while the controls had a mean age of 25 ± 3.99. The mean age at first pregnancy among cases was 20 ± 2.82 and among controls was 20 ± 2.97. The average number of deliveries for cases and controls was 1.97 ± 1.41 and 1.95 ± 1.38, respectively. There is no significant association between iron-folic acid supplementation and PIH. Pregnant women with high hemoglobin levels had higher odds of PIH as compared to those without it (AOR = 3.65; 95% CI: 1.0-12.9). Eating kocho (AOR = 14.4; 95% CI: 1.2-16.7) was positively associated with PIH.
There is no association between iron-folic acid supplementation during pregnancy and pregnancy-induced hypertension. Pregnant women with high hemoglobin levels had higher odds of PIH as compared to those without it. There is an association between kocho consumption and PIH. More research should be done using stronger designs.
妊娠高血压是指女性在妊娠 20 周后出现的血压升高，此前血压正常。据我们所知，我国尚未开展针对这一妊娠问题与叶酸铁补充剂之间关联的研究。本研究旨在确定沃莱塔索多地区公立医院孕妇中叶酸铁补充剂与妊娠高血压（PIH）之间的关联。
这是一项在 2022 年 3 月 3 日至 8 月 30 日期间在沃莱塔索多地区公立医院就诊的孕妇中进行的基于机构的病例对照研究。采用连续抽样方法选择研究参与者。总样本量为 492 人，其中 164 人为病例，328 人为对照。通过面对面访谈和测量收集数据。将数据录入 EpiData 版本 4.6 并导出到 STATA 14 进行分析。p 值小于 0.05 的变量被认为具有统计学意义。使用文本、表格和图形呈现描述性统计数据和优势比。
共有 471 名妇女参加了这项研究，应答率为 96%。病例组的平均年龄为 25 ± 4.43 岁，而对照组的平均年龄为 25 ± 3.99 岁。病例组的首次妊娠年龄平均为 20 ± 2.82 岁，对照组为 20 ± 2.97 岁。病例组和对照组的平均分娩次数分别为 1.97 ± 1.41 和 1.95 ± 1.38。叶酸铁补充与 PIH 之间无显著关联。与没有高血红蛋白水平的孕妇相比，血红蛋白水平较高的孕妇患 PIH 的几率更高（AOR=3.65；95%CI：1.0-12.9）。食用科乔（AOR=14.4；95%CI：1.2-16.7）与 PIH 呈正相关。
妊娠期间补充叶酸铁与妊娠高血压无关。与没有高血红蛋白水平的孕妇相比，血红蛋白水平较高的孕妇患 PIH 的几率更高。食用科乔与 PIH 有关。应使用更强的设计进行更多研究。
