Aĭzman R I, Velikanova L K, Pautova O M
Zh Evol Biokhim Fiziol. 1986 Mar-Apr;22(2):149-56.
In acute experiments on anaesthetized rats from three age groups (15-20, 25-30 days of postnatal life, adult ones), studies have been made on water basins of the organism after peroral injection of hypertonic (2.5-5%) solutions of NaCl (5 and 10 ml per 100 g of the body weight). It was demonstrated that during ontogenesis, total content of water decreases mainly at the expense of extracellular fluid. Infusion of saline solutions into the stomach of rats decreases fluid content in all water basins, especially in the interstitial one. The level of changes depends on the volume of the injected solution and, to a greater extent, on the concentration of the latter and the age of animals. The described response is due to osmotic transport of water into the alimentary tract, as suggested by the decrease of water content in this tract. The role of the digestive tract in osmotic and volume regulation during peroral salt loading is discussed.
在对三个年龄组（出生后15 - 20天、25 - 30天的幼鼠以及成年大鼠）的麻醉大鼠进行的急性实验中，在经口注射高渗（2.5 - 5%）氯化钠溶液（每100克体重注射5毫升和10毫升）后，对机体的水腔进行了研究。结果表明，在个体发育过程中，总含水量的减少主要是以细胞外液为代价的。向大鼠胃内输注盐溶液会降低所有水腔中的液体含量，尤其是间质液中的含量。变化程度取决于注射溶液的体积，在更大程度上还取决于溶液的浓度以及动物的年龄。如该消化道内含水量的减少所示，上述反应是由于水向消化道的渗透转运所致。文中讨论了消化道在经口摄入盐分期间渗透和容量调节中的作用。
