Näslund I
Acta Chir Scand. 1986 Mar;152:205-10.
In 57 consecutive morbidly obese patients randomized to gastric bypass (29) or gastroplasty (28) the stoma size was measured by a simple and reproducible endoscopical method at 2, 6 and 12 months postoperatively. The stomata enlarged with time but no difference in stoma size between the groups was observed. With gastroplasty at each measurement an increasing correlation, at one year statistically significant, was found between weight loss and stoma size. Gastroplasty patients with smaller stomata lost more weight than those with larger stomata. After gastric bypass no such correlation appeared but these patients lost more weight (42.3 kg versus 29.9 kg, p less than 0.001). This suggest that some additional factor regulating weight loss other than stoma size is at work in this method.
在57例连续入选的病态肥胖患者中,随机分为胃旁路手术组(29例)和胃成形术组(28例),术后2个月、6个月和12个月时,采用一种简单且可重复的内镜方法测量吻合口大小。吻合口随时间增大,但两组间吻合口大小无差异。对于胃成形术组,每次测量时均发现体重减轻与吻合口大小之间的相关性增加,在1年时具有统计学意义。吻合口较小的胃成形术患者比吻合口较大的患者体重减轻更多。胃旁路手术后未出现这种相关性,但这些患者体重减轻更多(42.3千克对29.9千克,p<0.001)。这表明在这种方法中,除吻合口大小外,还有一些其他调节体重减轻的因素在起作用。