Bloomston M, Zervos E E, Camps M A, Goode S E, Rosemurgy A S
University of South Florida College of Medicine, Division of Surgical Digestive Disorders, Tampa, USA.
Obes Surg. 1997 Oct;7(5):414-9. doi: 10.1381/096089297765555395.
Numerous investigators have attempted to identify prognostic indicators for successful outcome following bariatric surgery. The purpose of this study was to determine whether degree of obesity affects outcome in super obese [>225% ideal body weight (IBW)] versus morbidly obese patients (160-225% IBW) undergoing gastric restrictive/bypass procedures.
Since 1984, 157 patients underwent either gastric bypass or vertical banded gastroplasty. Super obese (78) and morbidly obese (79) patients were followed prospectively, documenting outcome and complications.
Super obese patients reached maximum weight loss 3 years following bariatric surgery, exhibiting a decrease in body mass index (BMI) from 61 to 39 kg/m2 and an average loss of 42% excess body weight (EBW). Morbidly obese patients had a decrease in BMI from 44 to 31 kg/m2 and carried 39% EBW at 1 year. After their respective nadirs, each group began to regain the lost weight with the super obese exhibiting a current BMI of 45 kg/m2 (61% EBW) versus 34 kg/m2 (52% EBW) in the morbidly obese at 72 months cumulative follow-up. Currently, loss of 50% or more of EBW occurred in 53% of super obese patients versus 72% of morbidly obese (P < 0.01). Twenty-six percent of super obese patients returned to within 50% of ideal body weight (IBW) while 71% of morbidly obese were able to reach this goal (P < 0.01). Co-morbidities and complications related to surgery were similar in each group.
Super obese patients have a greater absolute weight loss after bariatric surgery than do morbidly obese patients. Using commonly utilized measures of success based on weight, morbidly obese patients tend to have better outcomes following bariatric surgery.
众多研究者试图确定减肥手术后成功预后的指标。本研究的目的是确定肥胖程度是否会影响接受胃限制/旁路手术的超级肥胖患者(>225%理想体重[IBW])与病态肥胖患者(160 - 225% IBW)的预后。
自1984年以来,157例患者接受了胃旁路手术或垂直束带胃成形术。对超级肥胖(78例)和病态肥胖(79例)患者进行前瞻性随访,记录预后和并发症情况。
超级肥胖患者在减肥手术后3年达到最大体重减轻,体重指数(BMI)从61降至39 kg/m²,平均超重体重(EBW)减轻42%。病态肥胖患者在1年时BMI从44降至31 kg/m²,EBW为39%。在各自的最低点之后,每组都开始重新增加体重,在累计随访72个月时,超级肥胖患者目前的BMI为45 kg/m²(EBW为61%),而病态肥胖患者为34 kg/m²(EBW为52%)。目前,53%的超级肥胖患者EBW减轻了50%或更多,而病态肥胖患者为72%(P < 0.01)。26%的超级肥胖患者体重恢复到理想体重(IBW)的50%以内,而71%的病态肥胖患者能够达到这一目标(P < 0.01)。每组与手术相关的合并症和并发症相似。
减肥手术后,超级肥胖患者的绝对体重减轻比病态肥胖患者更大。使用基于体重的常用成功衡量标准,病态肥胖患者在减肥手术后往往有更好的预后。