成长：我们微生物的 NOD2。

Growing up: A NOD2 our microbes.

机构信息

Division of Pediatric Gastroenterology & Hepatology, Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

出版信息

Cell Host Microbe. 2023 May 10;31(5):685-687. doi: 10.1016/j.chom.2023.04.014.

DOI:10.1016/j.chom.2023.04.014

PMID:37167948

Abstract

In a recent report in Science, Schwarzer and colleagues demonstrate the growth benefits of treatment with Lactiplantibacillus plantarum strain WJL in a preclinical mouse model of chronic undernutrition. L. plantarum influences the somatotropic axis to promote growth through intestinal epithelial NOD2 sensing.

摘要

在最近发表于《科学》杂志的一篇报告中，Schwarzer 及其同事展示了植物乳杆菌 WJL 菌株在慢性营养不良的临床前小鼠模型中的治疗对生长的促进作用。植物乳杆菌通过肠道上皮 NOD2 感应影响生长激素轴来促进生长。