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瑞尔黑变病治疗的研究进展

Research Advances in the Treatment of Riehl's Melanosis.

作者信息

Xu Liuli, Huang Qing, Wu Ting, Mu Yunzhu

机构信息

Department of Dermatology, Affiliated Hospital of North Sichuan Medical College, Nanchong, People's Republic of China.

出版信息

Clin Cosmet Investig Dermatol. 2023 May 4;16:1181-1189. doi: 10.2147/CCID.S403090. eCollection 2023.

Abstract

Riehl's melanosis (RM) is a contact photodermatitis, with fast progressive gray-brown skin pigmentation as the main manifestation, which can seriously affect the psychology and physiology of patients. Currently, although the etiological factors of Riehl's melanosis is still be unknown, the existing literature proves clearly the cause of it is related to the contacting with suspected allergens. For decades, there has been no standard method for the treatment of RM, but with both conventional drug therapy and laser therapy having been attempted. Topical application of bleaching agents is mainly used as an auxiliary treatment modality. The laser treatment modality remains a hot spot, among which Q-switched Nd:YAG laser is well received for RM. Positive outcomes have been achieved by the combined treatment modalities attempted in recent years also achieve positive outcomes. The purpose of this paper is to review and summarize recent advances in the treatment of the disease.

摘要

里尔氏黑变病(RM)是一种接触性光皮炎,主要表现为快速进展的灰棕色皮肤色素沉着,可严重影响患者的心理和生理。目前,虽然里尔氏黑变病的病因仍不明,但现有文献明确证明其病因与接触可疑过敏原有关。几十年来,一直没有治疗RM的标准方法,但已尝试过传统药物治疗和激光治疗。外用漂白剂主要用作辅助治疗方式。激光治疗方式仍然是一个热点,其中调Q Nd:YAG激光治疗RM备受青睐。近年来尝试的联合治疗方式也取得了积极成果。本文的目的是回顾和总结该疾病治疗的最新进展。

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