Vinay Keshavamurthy, Bishnoi Anuradha, Kamat Divya, Chatterjee Debajyoti, Kumaran Muthu Sendhil, Parsad Davinder
Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian Dermatol Online J. 2021 Aug 2;12(5):663-673. doi: 10.4103/idoj.IDOJ_881_20. eCollection 2021 Sep-Oct.
Acquired dermal macular hyperpigmentation (ADMH) is an umbrella term that includes disorders clinically characterized by small and large pigmented macules/patches and histopathologically showing an evidence of current or resolved interface dermatitis with pigment incontinence, without clinically significant prior inflammatory phase. The term intends to include diseases previously described in the literature as lichen planus pigmentosus, Riehl's melanosis/pigmented cosmetic dermatitis and ashy dermatosis/erythema dyschromicum perstans. The nomenclature and origin of these disorders have always been a matter of discussion. These disorders share many clinicopathological similarities, are difficult to treat and adversely affect the quality of life. Recent consensus points towards the need for a unifying term to facilitate research and therapeutic trials. This article aims to provide a comprehensive review of the recent advances in ADMH.
获得性皮肤斑状色素沉着（ADMH）是一个统称，包括临床上以大小不一的色素沉着斑/斑片为特征，组织病理学显示有当前或已消退的界面性皮炎伴色素失禁证据，且临床上无明显先前炎症期的疾病。该术语旨在涵盖文献中先前描述为扁平苔藓样色素沉着、里尔黑变病/色素性化妆品皮炎以及灰皮病/持久性色素异常性红斑的疾病。这些疾病的命名和起源一直是讨论的话题。这些疾病有许多临床病理相似之处，难以治疗，且对生活质量有不利影响。最近的共识表明需要一个统一的术语来促进研究和治疗试验。本文旨在对ADMH的最新进展进行全面综述。
