Malhotra Neha, Lendner Nuphar, Gagliardo Christina, Breglio Keith, Mor Niv, Wetzler Graciela
Pediatric Gastroenterology, Maimonides Medical Center, Brooklyn, NY.
UH Rainbow Babies & Children's Hospital, Cleveland, OH.
JPGN Rep. 2022 Feb 25;3(2):e178. doi: 10.1097/PG9.0000000000000178. eCollection 2022 May.
Esophageal squamous papillomas (ESP) are rare benign tumors of the esophagus, which occur mostly in the adult population. Few cases have been reported in children and due to the low incidence, the pathogenesis of ESP is not entirely understood and the management is not standardized. It is thought that mucosal irritation from underlying inflammation, perhaps from GERD, trauma or human papilloma viruses can play a role in the formation of ESP. This report describes 4 cases of pediatric ESP from a single center and discusses the management of these lesions, including the use of antacids and the human papilloma viruses vaccine as treatment modalities. Given the limited data on ESP in the pediatric population, this report aims to describe the management of this condition in 1 center.
食管鳞状乳头状瘤(ESP)是食管罕见的良性肿瘤,多见于成人。儿童病例报道较少,由于发病率低,ESP的发病机制尚未完全明确,治疗也不规范。一般认为,潜在炎症(可能由胃食管反流病、创伤或人乳头瘤病毒引起)导致的黏膜刺激可能在ESP的形成中起作用。本报告描述了来自单一中心的4例儿童ESP病例,并讨论了这些病变的治疗方法,包括使用抗酸剂和人乳头瘤病毒疫苗作为治疗手段。鉴于儿科人群中关于ESP的数据有限,本报告旨在描述一个中心对这种疾病的治疗情况。