Seitz W S, McIlroy M B, Kline H, Operschall J, Kashani I A
Am Heart J. 1986 Jun;111(6):1118-22. doi: 10.1016/0002-8703(86)90015-3.
We have investigated the use of M-mode echocardiography for the diagnosis of aortic valve stenosis by application of the Gorlin formula. The hemodynamic parameters which enter this formula are shown to derive wholly from noninvasive measurements. The predicted valve areas correspond with those derived by classical catheterization studies at a level of r = 0.89, SE = 0.11 cm2, n = 10. These results suggest that the Gorlin formula for aortic stenosis may have application in a noninvasive context.