Takenaka K, Dabestani A, Gardin J M, Russell D, Clark S, Allfie A, Henry W L
Am J Cardiol. 1986 Jun 1;57(15):1340-3. doi: 10.1016/0002-9149(86)90215-8.
Doppler echocardiography is useful for detecting aortic regurgitation (AR). To determine if the presence of retrograde holodiastolic flow in the abdominal aorta can be used to assess the severity of AR, abdominal aortic flow velocity was examined by pulsed Doppler echocardiography in 33 patients with AR and 10 patients without AR confirmed by aortography, and in 15 normal subjects. Among the 33 patients with AR, 15 had mitral regurgitation, 11 had mitral stenosis, 8 had aortic stenosis, 5 had prosthetic mitral valves, 4 had prosthetic aortic valves and 2 had aorticopulmonary shunts. No retrograde holodiastolic flow was found in the abdominal aorta of 15 normal subjects or 10 patients without AR. Of the 22 patients with 1+ or 2+ AR independently determined by injection of iodinated contrast into the aortic root, 21 did not have retrograde holodiastolic abdominal aortic flow, whereas all 11 patients with 3+ or 4+ AR had retrograde holodiastolic flow in the abdominal aorta. One patient with 1+ AR and a left-to-right aorticopulmonary shunt had retrograde holodiastolic flow in the abdominal aorta. The finding of holodiastolic retrograde flow in the abdominal aorta is useful for distinguishing patients with severe AR from those with mild or absent AR. Moreover, the method is easy to perform and results appear to be independent of the presence of other cardiac diseases except significant aorticopulmonary shunt.
多普勒超声心动图对检测主动脉瓣反流(AR)很有用。为了确定腹主动脉舒张期全时逆向血流的存在是否可用于评估AR的严重程度,对33例经主动脉造影证实有AR的患者、10例经主动脉造影证实无AR的患者以及15名正常受试者进行了脉冲多普勒超声心动图检查,测量腹主动脉血流速度。在33例有AR的患者中,15例有二尖瓣反流,11例有二尖瓣狭窄,8例有主动脉瓣狭窄,5例有人工二尖瓣,4例有人工主动脉瓣,2例有主肺动脉分流。15名正常受试者和10例无AR的患者的腹主动脉均未发现舒张期全时逆向血流。在经主动脉根部注射碘化造影剂独立确定为1+或2+AR的22例患者中,21例腹主动脉无舒张期全时逆向血流,而所有11例3+或4+AR患者的腹主动脉均有舒张期全时逆向血流。1例有1+AR且存在左向右主肺动脉分流的患者腹主动脉有舒张期全时逆向血流。腹主动脉舒张期全时逆向血流的发现有助于将重度AR患者与轻度AR或无AR患者区分开来。此外,该方法易于实施,除了明显的主肺动脉分流外,结果似乎不受其他心脏疾病的影响。