Tani L Y, Minich L L, Day R W, Orsmond G S, Shaddy R E
Department of Pediatrics, Primary Children's Medical Center, and the University of Utah, Salt Lake City 84113, USA.
Am J Cardiol. 1997 Oct 1;80(7):927-31. doi: 10.1016/s0002-9149(97)00547-x.
Doppler indexes have been used successfully to determine the severity of aortic regurgitation (AR) in adults but have not been evaluated systematically in children. To evaluate the accuracy of specific Doppler echocardiographic indexes in assessing the degree of AR in children, 30 children underwent 2-dimensional and Doppler echocardiography within 24 hours of angiography. Patients were divided into 4 groups based on the degree of angiographic AR. Color Doppler jet width, short-axis jet area, jet length, and maximum jet area were measured. AR slope was measured using continuous-wave Doppler. Flow in the abdominal aorta was evaluated using pulsed Doppler. Doppler indexes were compared with the angiographic grade of AR. Jet width and short-axis jet area were significantly different between groups and showed strong correlation with the angiographic grade. Holodiastolic flow reversal in the abdominal aorta separated 1+ to 2+ from 3+ to 4+ AR (100% sensitivity and 100% negative predictive value for 3+ to 4+ AR). Jet length, maximum jet area, and the ratio of reverse to forward abdominal aortic velocity time integrals correlated with angiography but showed little difference between groups that differed by only 1 angiographic grade. AR slope did not correlate with the angiographic grade. We conclude that in children, color Doppler jet width, short-axis jet area, and holodiastolic abdominal aortic flow reversal are the best predictors of angiographic severity. Use of these indexes may obviate the need for angiography to determine the degree of AR in children.
多普勒指标已成功用于确定成人主动脉反流(AR)的严重程度,但尚未在儿童中进行系统评估。为了评估特定多普勒超声心动图指标在评估儿童AR程度方面的准确性,30名儿童在血管造影后24小时内接受了二维和多普勒超声心动图检查。根据血管造影AR的程度将患者分为4组。测量彩色多普勒射流宽度、短轴射流面积、射流长度和最大射流面积。使用连续波多普勒测量AR斜率。使用脉冲多普勒评估腹主动脉内的血流。将多普勒指标与AR的血管造影分级进行比较。射流宽度和短轴射流面积在各组之间有显著差异,并且与血管造影分级显示出很强的相关性。腹主动脉全舒张期血流逆转将1+至2+级AR与3+至4+级AR区分开来(对3+至4+级AR的敏感性为100%,阴性预测值为100%)。射流长度、最大射流面积以及腹主动脉反向与正向速度时间积分的比值与血管造影相关,但在仅相差1个血管造影分级的组之间差异很小。AR斜率与血管造影分级无关。我们得出结论,在儿童中,彩色多普勒射流宽度、短轴射流面积和腹主动脉全舒张期血流逆转是血管造影严重程度的最佳预测指标。使用这些指标可能无需进行血管造影来确定儿童AR的程度。