Department of Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Transfus Med. 2023 Aug;33(4):337-348. doi: 10.1111/tme.12972. Epub 2023 May 12.
Cardiac surgery is associated with numerous peri- and post-operative haemostatic complications and blood transfusion requirements. Complex procedures such as redo-sternotomy heart transplantation or type A aortic dissection repairs are at high-risk for severe coagulopathy and significant transfusion requirements. However, current practice guidelines do not specifically address high-risk surgeries, resulting in variable practice. To optimise outcomes, a multidisciplinary approach to blood transfusion and haemostasis is critical. How individual institutions construct these multidisciplinary teams, delegate responsibilities, and build procedures may differ depending on the institution and availability of resources. In this article, we compare how the transfusion medicine services support their cardiac surgery and transplant programs at three large medical centres-Vanderbilt University Medical Center (the largest heart transplant centre in the world by volume in 2021), Toronto General Hospital-University Health Network (a quaternary-care centre in Canada's most populous city, performing more >20 heart transplants annually), and Vancouver General Hospital (a quaternary-care centre that performs numerous high-risk cardiac surgeries). This article discusses management from multiple perspectives, including the blood bank and perioperative environments, and highlights how institutions have evolved their programs in accordance with nation-specific policies and provisions.
心脏手术与许多围手术期和术后止血并发症以及输血需求有关。心脏移植或 A 型主动脉夹层修复等复杂手术存在严重凝血障碍和大量输血需求的高风险。然而,目前的实践指南并没有专门针对高风险手术,导致实践存在差异。为了优化结果,采用多学科方法处理输血和止血至关重要。个体机构如何构建这些多学科团队、分配职责和制定程序可能因机构和资源的可用性而异。在本文中,我们比较了范德比尔特大学医学中心(2021 年按体积计算是全球最大的心脏移植中心)、多伦多综合医院-大学健康网络(加拿大人口最多的城市的四级保健中心,每年进行超过 20 例心脏移植)和温哥华总医院(一个进行大量高风险心脏手术的四级保健中心)的输血医学服务如何支持他们的心脏手术和移植项目。本文从多个角度讨论了管理问题,包括血库和围手术期环境,并强调了各机构如何根据国家特定的政策和规定来调整他们的项目。