College of Medicine, Northeast Ohio Medical University, Ohio, Rootstown, USA.
Department of Biochemistry and Molecular Biology, Johns Hopkins University Bloomberg School of Public Health, Maryland, Baltimore, USA.
Pigment Cell Melanoma Res. 2023 Sep;36(5):431-438. doi: 10.1111/pcmr.13090. Epub 2023 Apr 25.
Acral lentiginous melanoma (ALM) is a subtype of cutaneous melanoma notorious for poor outcomes that disproportionately affect individuals with skin of color (e.g., African-, Hispanic-, Asian-descent) when compared to mortality rates among non-Hispanic White populations. There are several societal factors that contribute to racial disparities in ALM, including a lack of representative educational material in the context of patient education and medical instruction. This gap in representative information for the US population includes risk of disease, patterns of incidence, and differences in disease presentation in skin of color. The atypical presentation of ALM on acral volar skin sites makes early detection challenging and necessitates an increased index of suspicion on the part of physicians and patients alike. Studies underscoring the importance of early detection in reducing mortality risk make the availability of adequate representative educational materials indispensable.
肢端雀斑样黑素瘤(ALM)是皮肤黑素瘤的一种亚型,其预后不良,与非西班牙裔白人人群的死亡率相比,皮肤颜色较深的个体(如非洲裔、西班牙裔、亚裔)的死亡率更高。导致 ALM 中存在种族差异的社会因素有很多,包括在患者教育和医学指导方面缺乏具有代表性的教育材料。美国人群中这种代表性信息的缺失包括疾病风险、发病模式以及皮肤颜色不同的疾病表现。肢端掌跖皮肤部位的 ALM 表现不典型,使得早期检测具有挑战性,这就需要医生和患者都提高警惕。强调早期检测对降低死亡率重要性的研究使得提供足够的有代表性的教育材料变得不可或缺。