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色素沉着皮肤中的黑色素瘤:第一部分。流行病学和临床表现。

Melanoma in skin of color: Part I. Epidemiology and clinical presentation.

机构信息

Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah.

Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah; Department of Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah.

出版信息

J Am Acad Dermatol. 2023 Sep;89(3):445-456. doi: 10.1016/j.jaad.2022.04.056. Epub 2022 May 6.

Abstract

Although there is a higher incidence of melanoma among non-Hispanic White individuals, melanoma is diagnosed at more advanced stages and associated with worse survival rates among individuals with skin of color (SOC). The proportions of melanoma subtypes differ across racial groups, with acral lentiginous melanoma and mucosal melanoma representing higher proportions of melanoma diagnoses in individuals with SOC compared to White individuals. The recognition of distinct differences in anatomic locations and dermatoscopic patterns may facilitate the appropriate differentiation of physiologic from pathologic pigmentation. The first article of this continuing medical education series will focus on the epidemiology and clinical presentation of melanoma in individuals with SOC, with the aim of improving early diagnoses and clinical outcomes.

摘要

尽管非西班牙裔白种人黑色素瘤的发病率较高,但在皮肤有色人种(SOC)中,黑色素瘤的诊断更为晚期,且与生存率较差相关。黑色素瘤亚型的比例在不同种族群体中存在差异,与白种人相比,SOC 中肢端黑色素瘤和黏膜黑色素瘤占黑色素瘤诊断的比例更高。对解剖部位和皮肤镜模式的明显差异的认识,可能有助于将生理性色素沉着与病理性色素沉着进行适当区分。本继续教育系列的第一篇文章将重点关注 SOC 人群中黑色素瘤的流行病学和临床表现,旨在改善早期诊断和临床结局。

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