Tan Charissa H, Tauchi-Nishi Pamela S, Sweeney Adam R
University of Hawai'i at Mānoa, John A. Burns School of Medicine, Honolulu, HI, USA.
Department of Pathology, University of Hawai'i at Mānoa, John A. Burns School of Medicine, Honolulu, HI, USA.
J Ophthalmic Inflamm Infect. 2023 May 12;13(1):24. doi: 10.1186/s12348-023-00349-y.
Epstein-Barr virus is a known cause of dacryoadenitis that is typically sensitive to corticosteroid treatment. When affecting the orbit, particularly the lacrimal gland, Epstein-Barr virus may cause chronic proptosis and a bilateral lacrimal mass effect. We provide a case of bilateral Epstein-Barr virus associated dacryoadenitis initially resistant to corticosteroid treatment requiring biopsy and confirmation by polymerase chain reaction of lacrimal tissue. Herein, we discuss the presentation with associated magnetic resonance imaging and histopathologic images, diagnostic dilemma, and treatment of an atypical case.
爱泼斯坦-巴尔病毒是泪腺炎的已知病因，通常对皮质类固醇治疗敏感。当累及眼眶，特别是泪腺时，爱泼斯坦-巴尔病毒可能导致慢性眼球突出和双侧泪腺肿块效应。我们报告一例双侧爱泼斯坦-巴尔病毒相关性泪腺炎病例，该病例最初对皮质类固醇治疗耐药，需要进行活检，并通过泪腺组织的聚合酶链反应进行确诊。在此，我们讨论该病例的临床表现以及相关的磁共振成像和组织病理学图像、诊断困境以及对这一非典型病例的治疗。
