Tian Guangyuan, Zhang Xuanzi, Hao Xiaoyan, Zhang Jianxin
College of Animal Science, Shanxi Agriculture University, Jinzhong 030801, China.
Animals (Basel). 2023 Apr 23;13(9):1439. doi: 10.3390/ani13091439.
This experiment was conducted to investigate growth performance, ruminal fermentation, rumen microbial protein synthesis, and serum antioxidant capacity with different doses of curcumin (CUR) included in the diet of housed growing lambs. Forty-eight four-month-old Dorper × Thin-tailed Han F crossbred male lambs (body weight = 20.89 ± 1.15 kg, age = 120 ± 10 days; mean ± SD) were randomly divided into four groups for a single-factor, completely randomized experiment. Treatments comprised the following: the basal diet supplemented with 0 (Control), 300 mg/kg (300 CUR), 600 mg/kg (600 CUR), or 900 mg/kg (900 CUR) CUR, respectively. The results showed that dietary CUR increased average daily gain (ADG), and the 300 CUR group evidenced the highest value. There were no significant effects on dry matter intake (DMI) and DMI/ADG. Lambs in the 300 CUR group showed higher totals of volatile fatty acids (VFA) and acetate than other groups, while decreased valerate was observed with supplementary CUR. The ruminal pH and ammonia N (NH-N) concentration decreased with increasing CUR, with the greatest effect in the 300 CUR group. The quadratic effects were found in pectinase, carboxymethyl cellulose, and protease, with the greatest value in the 300 CUR group. The microbial populations of total bacteria and also responded quadratically, and the methanogens, protozoan, and populations decreased linearly with increasing CUR. Lambs receiving additional CUR showed increased population. Microbial protein (MCP) synthesis was promoted by supplementary CUR. As supplementation with CUR increased, the serum activity of total antioxidant capacity (T-AOC), superoxide dismutase (SOD), and glutathione peroxidase (GSH-Px) was enhanced, with the greatest value in the 300 CUR group. In conclusion, dietary CUR improved ruminal fermentation, promoted rumen microbial protein (MCP) synthesis, and enhanced serum antioxidant activity, as well as promoting growth performance in housed growing lambs.
本试验旨在研究在舍饲生长羔羊日粮中添加不同剂量姜黄素（CUR）对其生长性能、瘤胃发酵、瘤胃微生物蛋白合成及血清抗氧化能力的影响。选取48只4月龄杜泊×小尾寒羊F1杂交公羔（体重=20.89±1.15 kg，年龄=120±10天；均值±标准差），随机分为4组进行单因素完全随机试验。处理组分别为：基础日粮分别添加0（对照组）、300 mg/kg（300 CUR）、600 mg/kg（600 CUR）或900 mg/kg（900 CUR）的CUR。结果表明，日粮添加CUR提高了平均日增重（ADG），其中300 CUR组的值最高。对干物质采食量（DMI）和DMI/ADG无显著影响。300 CUR组羔羊的挥发性脂肪酸（VFA）总量和乙酸含量高于其他组，而随着CUR添加量的增加，戊酸含量降低。瘤胃pH值和氨态氮（NH-N）浓度随CUR添加量的增加而降低，300 CUR组的影响最大。果胶酶、羧甲基纤维素酶和蛋白酶呈二次效应，300 CUR组的值最大。总细菌的微生物数量也呈二次响应，随着CUR添加量的增加，产甲烷菌、原生动物和 数量呈线性下降。添加CUR的羔羊 数量增加。补充CUR促进了微生物蛋白（MCP）的合成。随着CUR添加量的增加，血清总抗氧化能力（T-AOC）、超氧化物歧化酶（SOD）和谷胱甘肽过氧化物酶（GSH-Px）的活性增强，300 CUR组的值最大。综上所述，日粮添加CUR改善了瘤胃发酵，促进了瘤胃微生物蛋白（MCP）合成，增强了血清抗氧化活性，并促进了舍饲生长羔羊的生长性能。
