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镉、铅、慢性生理应激与子宫内膜癌:环境政策如何改变美国高危女性的暴露情况

Cadmium, Lead, Chronic Physiological Stress and Endometrial Cancer: How Environmental Policy Can Alter the Exposure of At-Risk Women in the United States.

作者信息

Olarewaju Elizabeth, Obeng-Gyasi Emmanuel

机构信息

Department of Built Environment, North Carolina A&T State University, Greensboro, NC 27411, USA.

Environmental Health and Disease Laboratory, North Carolina A&T State University, Greensboro, NC 27411, USA.

出版信息

Healthcare (Basel). 2023 Apr 29;11(9):1278. doi: 10.3390/healthcare11091278.

DOI:10.3390/healthcare11091278
PMID:37174820
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10178079/
Abstract

The health and life outcomes of individuals are intertwined with the context in which they grow and live. The totality of exposures one experiences affects health in the short term and throughout the life course. Environmental exposure to multiple contaminants can increase stress levels in individuals and neighborhoods with psychosocial stressors such as crime, drug and alcohol misuse, and violence also taking a toll on individual and neighborhood wellbeing. In addition, the availability, organization, and quality of local institutions and infrastructure all affect health in the short and long term. The role of these factors in endometrial cancer will be explored in this paper. In addition, policy implications regarding lead, chronic physiological stress, and endometrial cancer will be explored to ascertain the impact of these factors on at-risk women.

摘要

个人的健康和生活结局与他们成长和生活的环境相互交织。一个人所经历的所有暴露在短期和整个生命历程中都会影响健康。接触多种环境污染物会增加个人和社区的压力水平,诸如犯罪、药物和酒精滥用以及暴力等社会心理压力源也会对个人和社区的福祉造成损害。此外,当地机构和基础设施的可及性、组织情况和质量在短期和长期都会影响健康。本文将探讨这些因素在子宫内膜癌中的作用。此外,还将探讨有关铅、慢性生理压力和子宫内膜癌的政策影响,以确定这些因素对高危女性的影响。

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本文引用的文献

1
Current Approaches to the Management of Patients with Endometrial Cancer.子宫内膜癌患者的当前管理方法
Cancers (Basel). 2022 Sep 16;14(18):4500. doi: 10.3390/cancers14184500.
2
An Integrated Approach for the Early Detection of Endometrial and Ovarian Cancers (Screenwide Study): Rationale, Study Design and Pilot Study.子宫内膜癌和卵巢癌早期检测的综合方法(Screenwide研究):原理、研究设计与初步研究
J Pers Med. 2022 Jun 29;12(7):1074. doi: 10.3390/jpm12071074.
3
Association of Allostatic Load and All Cancer Risk in the SWAN Cohort.SWAN队列中应激负荷与所有癌症风险的关联。
Cancers (Basel). 2022 Jun 21;14(13):3044. doi: 10.3390/cancers14133044.
4
Should Endometrial Cancer Treatment Be Centralized?子宫内膜癌治疗应集中化吗?
Biology (Basel). 2022 May 18;11(5):768. doi: 10.3390/biology11050768.
5
Health outcomes in redlined versus non-redlined neighborhoods: A systematic review and meta-analysis.红线社区与非红线社区的健康结果比较:系统评价和荟萃分析。
Soc Sci Med. 2022 Feb;294:114696. doi: 10.1016/j.socscimed.2021.114696. Epub 2021 Dec 31.
6
Environmental and occupational exposure of metals and female reproductive health.环境和职业暴露于金属与女性生殖健康。
Environ Sci Pollut Res Int. 2022 Sep;29(41):62067-62092. doi: 10.1007/s11356-021-16581-9. Epub 2021 Sep 24.
7
A Narrative Review of the Role of Diet and Lifestyle Factors in the Development and Prevention of Endometrial Cancer.饮食和生活方式因素在子宫内膜癌发生与预防中作用的叙述性综述
Cancers (Basel). 2021 Apr 29;13(9):2149. doi: 10.3390/cancers13092149.
8
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020:全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
9
ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma.ESGO/ESTRO/ESP 子宫内膜癌管理指南。
Int J Gynecol Cancer. 2021 Jan;31(1):12-39. doi: 10.1136/ijgc-2020-002230. Epub 2020 Dec 18.
10
Chronic Stress Promotes Cancer Development.慢性应激促进癌症发展。
Front Oncol. 2020 Aug 19;10:1492. doi: 10.3389/fonc.2020.01492. eCollection 2020.