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试点研究:高压氧疗法治疗2型糖尿病患者牙周炎的有效性

Pilot Study: The Effectiveness of Hyperbaric Oxygen Therapy in the Treatment of Periodontitis in Patients with Type 2 Diabetes.

作者信息

Latusek Katarzyna, Słotwińska-Pawlaczyk Adrianna, Warakomska Aleksandra, Kubicka-Musiał Magdalena, Wiench Rafał, Orzechowska-Wylęgała Bogusława

机构信息

Department of Pediatric Otolaryngology, Head and Neck Surgery, Chairs of Pediatric Surgery, The Independent Public Clinical Hospital No. 6 of the Medical University of Silesia in Katowice, John Paul II Upper Silesian Child Health Centre, 40-055 Katowice, Poland.

Department of Periodontal Diseases and Oral Mucosa Diseases, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Pl. Traugutta 2, 41-800 Zabrze, Poland.

出版信息

Healthcare (Basel). 2023 May 7;11(9):1344. doi: 10.3390/healthcare11091344.

DOI:10.3390/healthcare11091344
PMID:37174886
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10178066/
Abstract

Periodontitis is a chronic inflammatory disease with multifactorial aetiology. The relationship between periodontal disease and systemic diseases such as diabetes, obesity, metabolic syndrome, atherosclerotic, cardiovascular disease, and cognitive disorders has been the subject of many studies. The purpose of this study was to evaluate the effectiveness of hyperbaric oxygen therapy on periodontal health in patients suffering from periodontitis and type 2 diabetes. The study was conducted with 14 patients. A total of 369 periodontal pockets in the study group and 431 in the control group were examined. For further analysis, the pockets were classified as moderately deep (4-5 mm) and deep (≥6 mm). All patients received standard non-surgical treatment: scaling and root planing (SRP). Additionally, a series of 30 hyperbaric chamber sessions was carried out in the study group. The following parameters were compared between groups: PD (probing depth), CAL (clinical attachment level), and BOP (bleeding on probing). The results of the study showed significantly better results in terms of PD reduction and CAL gain in the study group in comparison to the control group. Both groups showed a reduction in BOP (bleeding on probing) after treatment. The use of hyperbaric oxygen therapy seems to have considerable benefits in patients with type 2 diabetes.

摘要

牙周炎是一种病因多因素的慢性炎症性疾病。牙周疾病与诸如糖尿病、肥胖症、代谢综合征、动脉粥样硬化、心血管疾病及认知障碍等全身性疾病之间的关系一直是众多研究的主题。本研究的目的是评估高压氧疗法对患有牙周炎和2型糖尿病患者牙周健康的有效性。该研究对14名患者进行。研究组共检查了369个牙周袋,对照组检查了431个。为进一步分析,将牙周袋分为中度深度(4 - 5毫米)和深度(≥6毫米)。所有患者均接受标准非手术治疗:龈上洁治和根面平整(SRP)。此外,研究组进行了一系列30次高压氧舱治疗。比较了两组之间的以下参数:牙周袋深度(PD)、临床附着水平(CAL)和探诊出血(BOP)。研究结果显示,与对照组相比,研究组在减少牙周袋深度和增加临床附着水平方面有显著更好的结果。两组治疗后探诊出血均减少。高压氧疗法的使用似乎对2型糖尿病患者有相当大的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60da/10178066/d509e59c7e73/healthcare-11-01344-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60da/10178066/d509e59c7e73/healthcare-11-01344-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60da/10178066/d509e59c7e73/healthcare-11-01344-g001.jpg

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本文引用的文献

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Effects of hyperbaric oxygen therapy on periodontal disease: a literature review.
Undersea Hyperb Med. 2023 First Quarter;50(1):17-27. doi: 10.22462/01.01.2023.17.
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Periodontitis and diabetes.牙周炎与糖尿病。
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Staging and grading of periodontitis: Framework and proposal of a new classification and case definition.牙周炎的分期和分级:新分类和病例定义的框架和建议。
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