Department of Mathematics, Faculty of Science, Ghazi University, Dera Ghazi Khan 32200, Pakistan.
Institute of Mathematics, Khawaja Fareed University of Engineering & Information Technology, Abu Dhabi Road, Rahim Yar Khan 64200, Pakistan.
Molecules. 2023 Apr 24;28(9):3684. doi: 10.3390/molecules28093684.
Due to significant advancements being made in the field of drug design, the use of topological descriptors remains the primary approach. When combined with QSPR models, descriptors illustrate a molecule's chemical properties numerically. Numbers relating to chemical composition topological indices are structures that link chemical composition to physical characteristics. This research concentrates on the analysis of curvilinear regression models and degree-based topological descriptors for thirteen skin cancer drugs. The physicochemical characteristics of the skin cancer drugs are examined while regression models are built for computed index values. An analysis is performed for several significant results based on the acquired data.
由于药物设计领域取得了重大进展，拓扑描述符的使用仍然是主要方法。当与 QSPR 模型结合使用时，描述符以数值形式表示分子的化学性质。与化学组成拓扑指数相关的数字是将化学组成与物理特性联系起来的结构。本研究集中于分析十三种皮肤癌药物的曲线回归模型和基于度数的拓扑描述符。在为计算出的指数值构建回归模型的同时，研究了皮肤癌药物的物理化学特性。根据所获得的数据，对几个重要结果进行了分析。
Zotero 插件
