King Ebony, Bazargan Mohsen, Entsuah Nana, Tokumitsu Sayaka W, Wisseh Cheryl, Adinkrah Edward K
Department of Geriatrics, West Los Angeles VA Medical Center, Los Angeles, CA 90073, USA.
Department of Public Health, Charles R. Drew University of Medicine and Science (CDU), Los Angeles, CA 90059, USA.
J Clin Med. 2023 Apr 23;12(9):3067. doi: 10.3390/jcm12093067.
Previous studies identified alarming increases in medication use, polypharmacy, and the use of potentially inappropriate medications (PIMs) among minority older adults with multimorbidity. However, PIM use among underserved older Latino adults is still largely unknown. The main objective of this study is to examine the prevalence of PIM use among underserved, community-dwelling older Latino adults. This study examines both the complexity of polypharmacy in this community and identifies associations between PIM and multimorbidity, polypharmacy, and access to medical care among this segment of our population.
This community-based, cross-sectional study included 126 community-dwelling Latinos aged 65 years and older. The updated 2019 AGS Beers Criteria was used to identify participants using PIMs. We used multinomial logistic regression to examine the independent association of PIM with several independent variables including demographic characteristics, the number of chronic conditions, the number of prescription medications used, level of pain, and sleep difficulty. In addition, we present five cases in order to offer greater insight into PIM use among our sample.
One-third of participants had at least one use of PIM. Polypharmacy (≥5 medications) was observed in 55% of our sample. In addition, 46% took drugs to be used with caution (UWC). In total, 16% were taking between 9 and 24 medications, whereas 39% and 46% were taking 5 to 8 and 1 to 4 prescription medications, respectively. The multinomial logit regression analysis showed that (controlling for demographic variables) increased PIM use was associated with an increased number of prescription medications, number of chronic conditions, sleep difficulty, lack of access to primary care, financial strains, and poor self-rated health.
Both qualitative and quantitative analysis revealed recurrent themes in the missed identification of potential drug-related harm among underserved Latino older adults. Our data suggest that financial strain, lack of access to primary care, as well as an increased number of medications and co-morbidity are inter-connected. Lack of continuity of care often leads to fragmented care, putting vulnerable patients at risk of polypharmacy and drug-drug interactions as clinicians lack access to a current and complete list of medications patients are using at any given time. Therefore, improving access to health care and thereby continuity of care among older Latino adults with multimorbidity has the potential to reduce both polypharmacy and PIM use. Programs that increase access to regular care and continuity of care should be prioritized among multimorbid, undeserved, Latino older adults in an effort toward improved health equity.
先前的研究发现,患有多种疾病的少数族裔老年人在药物使用、多重用药以及使用潜在不适当药物(PIMs)方面出现了惊人的增长。然而,在服务不足的老年拉丁裔成年人中,PIMs的使用情况仍 largely unknown。本研究的主要目的是调查服务不足的社区居住老年拉丁裔成年人中PIMs的使用 prevalence。本研究考察了该社区多重用药的复杂性,并确定了PIM与多重疾病、多重用药以及我们这部分人群获得医疗服务之间的关联。
这项基于社区的横断面研究纳入了126名年龄在65岁及以上的社区居住拉丁裔。使用更新后的2019年美国老年医学会(AGS)Beers标准来识别使用PIMs的参与者。我们使用多项逻辑回归来检验PIM与几个自变量之间的独立关联,这些自变量包括人口统计学特征、慢性病数量、使用的处方药数量、疼痛程度和睡眠困难。此外,我们展示了五个案例,以便更深入地了解我们样本中PIMs的使用情况。
三分之一的参与者至少有一次使用PIM。我们样本中有55%观察到多重用药(≥5种药物)。此外,46%的人服用需谨慎使用的药物(UWC)。总共有16%的人服用9至24种药物,而39%和46%的人分别服用5至8种和1至4种处方药。多项logit回归分析表明(控制人口统计学变量),PIM使用增加与处方药数量增加、慢性病数量、睡眠困难、无法获得初级保健、经济压力以及自我健康评分差有关。
定性和定量分析都揭示了在服务不足的拉丁裔老年人中,潜在药物相关危害未被识别的反复出现的主题。我们的数据表明,经济压力、无法获得初级保健,以及药物数量增加和共病是相互关联的。缺乏连续性护理往往导致护理碎片化,使弱势患者面临多重用药和药物相互作用的风险,因为临床医生无法随时获取患者正在使用的当前完整药物清单。因此,改善患有多种疾病的老年拉丁裔成年人获得医疗保健的机会,从而提高护理的连续性,有可能减少多重用药和PIM的使用。在患有多种疾病、服务不足的拉丁裔老年人中,应优先考虑增加获得常规护理和护理连续性的项目,以努力改善健康公平性。