Demeter S L
Angiology. 1986 Apr;37(4):325-38. doi: 10.1177/000331978603700410.
Six patients with interstitial lung disease were tested in a serial fashion to determine response to medications. All patients had biopsy-proven interstitial lung disease. Exercise testing with measurements of PaO2, PaCO2, and DLCO (the diffusing capacity to carbon monoxide) were made before and after exercise to determine the response to medications. Three patients were treated with corticosteroids and three patients with cytotoxic medications. Results of serial testing of gas transfer correlated with improvement of interstitial lung disease as characterized by resting PaO2, symptoms, and maximal duration of exercise. The value of serial exercise testing is of great help in some, but not all patients. The value of serial testing of patients with interstitial lung disease is discussed.
对六名间质性肺病患者进行了一系列测试，以确定其对药物的反应。所有患者均经活检证实患有间质性肺病。在运动前后进行运动测试，测量动脉血氧分压（PaO2）、动脉血二氧化碳分压（PaCO2）和一氧化碳弥散量（DLCO），以确定对药物的反应。三名患者接受了皮质类固醇治疗，三名患者接受了细胞毒性药物治疗。气体交换的系列测试结果与间质性肺病的改善相关，其特征为静息PaO2、症状和最大运动持续时间。系列运动测试对部分但并非所有患者有很大帮助。本文讨论了间质性肺病患者系列测试的价值。
