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伴有心脏受累及膜外肾小球病的血液嗜酸性粒细胞增多综合征

[Blood hypereosinophilia syndrome with cardiac involvement and extramembranous glomerulopathy].

作者信息

Lanfranchi J, Meyrier A, Sachs R N, Guillevin L

出版信息

Ann Med Interne (Paris). 1986;137(2):133-7.

PMID:3717818
Abstract

The case of a 71 year old woman with an idiopathic hypereosinophilic syndrome is reported. Bidimensional ultrasonography was in favor of endomyocardial involvement. This case was original as nephrotic syndrome developed, due to membranous glomerulopathy which was complicated with renal vein thrombosis. Both eosinophilia and nephrotic syndrome greatly improved with corticosteroid treatment. Nonetheless, the patient died suddenly after 2 years, and this demise is in keeping with the overall poor prognosis of idiopathic eosinophilic syndrome.

摘要

报告了一例71岁患有特发性嗜酸性粒细胞增多综合征的女性病例。二维超声心动图显示有心肌内膜受累。该病例的独特之处在于,由于膜性肾小球病并发肾静脉血栓形成,进而发展为肾病综合征。使用皮质类固醇治疗后,嗜酸性粒细胞增多和肾病综合征均有显著改善。尽管如此,患者在2年后突然死亡,这与特发性嗜酸性粒细胞综合征总体预后较差相符。

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