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行单节段关节置换术与前路腰椎间融合术患者的结局。

Outcomes of patients undergoing single-level arthroplasty versus anterior lumbar interbody fusion.

机构信息

Department of Neurosurgery, University of Illinois at Chicago, 912 South Wood Street, 451N - MC 799, Chicago, IL, 60612, USA.

Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.

出版信息

Acta Neurochir (Wien). 2023 Jul;165(7):1915-1921. doi: 10.1007/s00701-023-05616-4. Epub 2023 May 13.

Abstract

BACKGROUND

Compared to vertebral body fusion, artificial discs are thought to lessen the risks of adjacent segment disease and the need for additional surgery by maintaining spinal mobility as they mimic the intervertebral disc structure. No studies have compared the rates of postoperative complications and the requirement for secondary surgery at adjacent segments among patients who have undergone anterior lumbar interbody fusions (ALIF) versus those undergoing lumbar arthroplasty.

METHODS

An all-payer claims database identified 11,367 individuals who underwent single-level ALIF and lumbar arthroplasty for degenerative disc disease (DDD) between January 2010 and October 2020. Rates of complications following surgery, the need for additional lumbar surgeries, length of stay (LOS), and postoperative opioid utilization were assessed in matched cohorts based on logistic regression models. Kaplan-Meyer plots were created to model the probability of additional surgery.

RESULTS

Following 1:1 exact matching, 846 records of patients who had undergone ALIF or lumbar arthroplasty were analyzed. All-cause readmission within 30-30 days following surgery was significantly higher in patients undergoing ALIF versus arthroplasty (2.6% vs. 0.71%, p = 0.02). LOS was significantly lower among the patients who had undergone ALIF (1.043 ± 0.21 vs. 2.17 ± 1.7, p < .001).

CONCLUSIONS

ALIF and lumbar arthroplasty procedures are equally safe and effective in treating DDD. Our findings do not support that single-level fusions may biomechanically necessitate revisional surgeries.

摘要

背景

相较于椎体融合术,人工椎间盘通过维持脊柱活动度来模拟椎间盘结构,被认为可以降低邻近节段疾病的风险和对额外手术的需求。但目前还没有研究比较接受前路腰椎间融合术(ALIF)与腰椎关节置换术的患者术后并发症发生率和邻近节段再次手术的需求。

方法

利用全支付者索赔数据库,在 2010 年 1 月至 2020 年 10 月期间,确定了 11367 名接受单节段 ALIF 和腰椎关节置换术治疗退行性椎间盘疾病(DDD)的患者。根据逻辑回归模型,在匹配队列中评估术后并发症发生率、需要额外腰椎手术、住院时间(LOS)和术后阿片类药物使用情况。采用 Kaplan-Meier 图来建立额外手术概率模型。

结果

在进行 1:1 精确匹配后,分析了 846 例接受 ALIF 或腰椎关节置换术的患者记录。术后 30-30 天内的全因再入院率,ALIF 组显著高于关节置换组(2.6%比 0.71%,p=0.02)。ALIF 组的 LOS 显著低于关节置换组(1.043±0.21 比 2.17±1.7,p<0.001)。

结论

ALIF 和腰椎关节置换术在治疗 DDD 方面同样安全有效。我们的研究结果并不支持单节段融合术可能在生物力学上需要进行翻修手术。

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