Weissler M C, Montgomery W W, Turner P A, Montgomery S K, Joseph M P
Ann Otol Rhinol Laryngol. 1986 May-Jun;95(3 Pt 1):215-21. doi: 10.1177/000348948609500301.
Two hundred twenty-three cases of inverted papilloma seen at this institution over a 35-year period were reviewed. The number of cases steadily increased over each 5-year period. Common presenting signs and symptoms, association with carcinoma, and results of surgical and radiographic treatment are presented. The pathologic controversy surrounding this disease is discussed, and an argument is made for including all pathologic subtypes and septal, lateral wall, or sinus cases in a common clinical grouping of inverted papilloma. Lateral rhinotomy was found to be associated with fewer recurrences and a better probability of cure than lesser procedures and is recommended as the standard surgical therapy. Radiotherapy was found to be a useful and effective adjunct in cases associated with malignancy or for multiply recurrent and inoperable benign inverted papillomas. Lifelong follow-up is urged.
回顾了本机构在35年期间所见的223例内翻性乳头状瘤病例。病例数在每5年期间稳步增加。介绍了常见的临床表现、与癌的关联以及手术和影像学治疗结果。讨论了围绕该疾病的病理争议，并主张将所有病理亚型以及鼻中隔、侧壁或鼻窦病例纳入内翻性乳头状瘤的共同临床分组。发现外侧鼻切开术与较少的复发相关，治愈概率高于较小的手术，因此推荐作为标准手术治疗方法。发现放射治疗在与恶性肿瘤相关的病例中，或对于多次复发且无法手术的良性内翻性乳头状瘤是一种有用且有效的辅助治疗方法。强烈建议进行终身随访。
