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Alloxan-induced changes in the collagen characteristics in the skin of male garden lizards, Calotes versicolor, from three age groups.

作者信息

Mishra G, Behera H N

出版信息

Arch Gerontol Geriatr. 1986 Apr;5(1):11-9. doi: 10.1016/0167-4943(86)90003-8.

DOI:10.1016/0167-4943(86)90003-8
PMID:3718067
Abstract

Alloxan diabetes in lizards Calotes versicolor, belonging to three age groups, induced decreased levels of percentage of solubility of collagen in dorsal and ventral skin regions after 7 days of treatment. Old lizards showed greater susceptibility to alloxan diabetes than lizards of the young and middle-age groups. There appears to be no correlation between blood-glucose level and accelerated ageing of collagen. It is suggested that, in alloxan diabetes, metabolites formed in the tissues might accelerate the ageing of collagen.

摘要

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