Shirazi Maryam, Qazvini Fatemeh Fotoohi, Mohamadrezaie Saeed
Private Dental Office, Qazvin, Iran.
Department of Microbiology, Qazvin University of Medical Sciences, Qazvin, Iran.
Dent Res J (Isfahan). 2023 Mar 28;20:45. eCollection 2023.
The aim of this study was to assess the effect of incorporation of zinc oxide nanoparticles (ZnO-NPs) to glass-ionomer cement (GIC) (Fuji II SC, GC Corp., Tokyo, Japan) on subgingival accumulation of mutans streptococci and lactobacilli under orthodontic bands.
In order to conduct this split-mouth study, 20 patients aged between 7 and 10 years who required lingual holding arch on their mandibular first molars were divided into two groups. In one group, Fuji II SC GIC was used for cementation of the right molar band, and the same cement containing 2 wt% ZnO-NPs was used for the left one. The opposite was performed for the second group while the operator was blinded to the cement types. Subgingival microbial sampling was performed 16 weeks after cementation of lingual arch. Mutans streptococci and lactobacilli colony counts were compared. Paired -test was used to compare the two cement groups. Data were analyzed using SPSS version 21, and ≤ 0.05 was considered statistically significant.
The mean colony counts of mutans streptococci, lactobacilli, and total bacterial count in Fuji II SC containing ZnO-NPs were significantly lower than the corresponding values in plain Fuji II SC group.
Incorporation of ZnO-NPs into GIC reveals antimicrobial features against mutans streptococci and lactobacilli under orthodontic bands.
本研究的目的是评估将氧化锌纳米颗粒（ZnO-NPs）掺入玻璃离子水门汀（GIC）（Fuji II SC，日本东京GC公司）对正畸带环下变形链球菌和乳酸菌龈下积聚的影响。
为进行这项双侧对照研究，将20例年龄在7至10岁之间、下颌第一磨牙需要舌弓保持器的患者分为两组。一组中，右侧磨牙带环用Fuji II SC GIC黏固，左侧磨牙带环用含2 wt% ZnO-NPs的相同水门汀黏固。第二组则相反，而操作者对水门汀类型不知情。在舌弓黏固16周后进行龈下微生物采样。比较变形链球菌和乳酸菌的菌落计数。采用配对t检验比较两组水门汀。数据使用SPSS 21版进行分析，P≤0.05被认为具有统计学意义。
含ZnO-NPs的Fuji II SC中变形链球菌、乳酸菌的平均菌落计数及总细菌计数均显著低于普通Fuji II SC组的相应值。
将ZnO-NPs掺入GIC可显示出对正畸带环下变形链球菌和乳酸菌的抗菌特性。
