Ye Sheng-Lin, Xiang Guang-Yuan, Liu Zhao, Li Wen-Dong, Tang Tao, Qian Ai-Min, Li Xiao-Qiang, Sun Li-Li
Department of Vascular Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Department of Vascular Surgery, Nanjing Drum Tower Hospital Clinical College of Jiangsu University, Nanjing, China.
Front Cardiovasc Med. 2023 Apr 27;10:1129255. doi: 10.3389/fcvm.2023.1129255. eCollection 2023.
Ruptured abdominal aortic aneurysms (rAAAs) are challenging for vascular surgeons because they have a high mortality rate. In many diseases, nutritional status is closely associated with prognosis. The Controlling Nutritional Status (CONUT) screening tool score is a prognostic factor in some malignant and chronic diseases; however, the impact of nutritional status on rAAA has not yet been reported. In this study, we explored the relationship between the CONUT score and the postoperative prognosis of patients with rAAA.
This was a retrospective review of 39 patients with rAAA who underwent surgical treatment from March 2018 to September 2021 at one center. Patient characteristics, nutritional status (CONUT score), and postoperative status were recorded. The patients were divided into groups A and B based on the CONUT score. The baseline characteristics of the two groups were compared, and Cox proportional hazards and logistic regression analyses were used to determine independent predictors of mid-term mortality and complications, respectively.
The overall mid-term mortality rate was 28.21% (11/39). Compared with group A, group B had higher intraoperative ( = 0.047) and mid-term mortality ( = 0.033) rates. The univariate analysis showed that age [hazard ratio (HR), 1.098; 95% confidence interval (CI), 1.019-1.182; = 0.014], CONUT score (HR, 1.316; 95% CI, 1.027-1.686; = 0.03), and surgical procedure (HR, 0.127; 95% CI, 0.016-0.992; = 0.049) were associated with mid-term mortality, whereas the multivariate analysis showed that the CONUT score (HR, 1.313; 95% CI, 1.009-1.710; = 0.043) was an independent predictor of mid-term mortality. The multivariate logistic regression analysis did not reveal any associations with complications. The Kaplan-Meier curves showed that group B had a lower mid-term survival rate (log-rank = 0.024).
Malnutrition is closely associated with the prognosis of patients with rAAA, and the CONUT score can be used to predict mid-term mortality.
破裂性腹主动脉瘤（rAAA）对血管外科医生来说是一项挑战，因为其死亡率很高。在许多疾病中，营养状况与预后密切相关。控制营养状况（CONUT）筛查工具评分是一些恶性和慢性疾病的预后因素；然而，营养状况对rAAA的影响尚未见报道。在本研究中，我们探讨了CONUT评分与rAAA患者术后预后之间的关系。
这是一项对2018年3月至2021年9月在一个中心接受手术治疗的39例rAAA患者的回顾性研究。记录患者的特征、营养状况（CONUT评分）和术后状况。根据CONUT评分将患者分为A组和B组。比较两组的基线特征，并分别采用Cox比例风险模型和逻辑回归分析来确定中期死亡率和并发症的独立预测因素。
总体中期死亡率为28.21%（11/39）。与A组相比，B组的术中死亡率（=0.047）和中期死亡率（=0.033）更高。单因素分析显示，年龄[风险比（HR），1.098；95%置信区间（CI），1.019 - 1.182；=0.014]、CONUT评分（HR，1.3
