El-Azazy Marwa, El-Shafie Ahmed S, Al-Mulla Reem, Hassan Siham S, Nimir Hassan I
Department of Chemistry and Earth Sciences, College of Arts and Sciences, Qatar University, Doha, 2713, Qatar.
Heliyon. 2023 Apr 26;9(5):e15802. doi: 10.1016/j.heliyon.2023.e15802. eCollection 2023 May.
Pharmaceutically active compounds (PhACs) represent an emerging class of contaminants. With a potential to negatively impact human health and the ecosystem, existence of pharmaceuticals in the aquatic systems is becoming a worrying concern. Antibiotics is a major class of PhACs and their existence in wastewater signifies a health risk on the long run. With the purpose of competently removing antibiotics from wastewater, cost-effective, and copiously available waste-derived adsorbents were structured. In this study, mango seeds kernel (MSK), both as a pristine biochar (Py-MSK) and as a nano-ceria-laden (Ce-Py-MSK) were applied for the remediation of rifampicin (RIFM) and tigecycline (TIGC). To save time and resources, adsorption experiments were managed using a multivariate-based scheme executing the fractional factorial design (FrFD). Percentage removal (%R) of both antibiotics was exploited in terms of four variables: pH, adsorbent dosage, initial drug concentration, and contact time. Preliminary experiments showed that Ce-Py-MSK has higher adsorption efficiency for both RIFM and TIGC compared to Py-MSK. The %R was 92.36% for RIFM compared to 90.13% for TIGC. With the purpose of comprehending the adsorption process, structural elucidation of both sorbents was performed using FT-IR, SEM, TEM, EDX, and XRD analyses which confirmed the decoration of the adsorbent surface with the nano-ceria. BET analysis revealed that Ce-Py-MSK has a higher surface area (33.83 m/g) contrasted to the Py-MSK (24.72 m/g). Isotherm parameters revealed that Freundlich model best fit Ce-Py-MSK-drug interactions. A maximum adsorption capacity () of 102.25 and 49.28 mg/g was attained for RIFM and TIGC, respectively. Adsorption kinetics for both drugs conformed well with both pseudo-second order (PSO) and Elovich models. This study, therefore, has established the suitability of Ce-Py-MSK as a green, sustainable, cost-effective, selective, and efficient adsorbent for the treatment of pharmaceutical wastewater.
具有药物活性的化合物（PhACs）是一类新兴的污染物。由于有可能对人类健康和生态系统产生负面影响，水生系统中药物的存在正成为一个令人担忧的问题。抗生素是PhACs的主要类别，它们在废水中的存在从长远来看意味着健康风险。为了有效地从废水中去除抗生素，制备了具有成本效益且大量可得的废物衍生吸附剂。在本研究中，芒果籽仁（MSK）作为原始生物炭（Py-MSK）和负载纳米氧化铈的材料（Ce-Py-MSK）被用于修复利福平（RIFM）和替加环素（TIGC）。为了节省时间和资源，吸附实验采用基于多变量的方案，执行分数因子设计（FrFD）。两种抗生素的去除率（%R）根据四个变量进行考察：pH值、吸附剂用量、初始药物浓度和接触时间。初步实验表明，与Py-MSK相比，Ce-Py-MSK对RIFM和TIGC都具有更高的吸附效率。RIFM的%R为92.36%，而TIGC为90.13%。为了理解吸附过程，使用傅里叶变换红外光谱（FT-IR）、扫描电子显微镜（SEM）、透射电子显微镜（TEM）、能量散射X射线光谱（EDX）和X射线衍射（XRD）分析对两种吸附剂进行了结构解析，证实了吸附剂表面有纳米氧化铈修饰。比表面积分析表明，Ce-Py-MSK的比表面积（33.83 m²/g）高于Py-MSK（24.72 m²/g）。等温线参数表明，Freundlich模型最适合Ce-Py-MSK与药物之间的相互作用。RIFM和TIGC的最大吸附容量（qm）分别达到102.25和49.28 mg/g。两种药物的吸附动力学与伪二级动力学（PSO）模型和埃洛维奇模型都很好地符合。因此，本研究确定了Ce-Py-MSK作为一种绿色、可持续、具有成本效益、选择性和高效的吸附剂用于处理制药废水的适用性。
