Fighting fire with fire: engineering a microbe into a therapeutic defense against drug-resistant biofilms.
作者信息
Cialek Charlotte Ayn
机构信息
Inscripta Inc., Boulder, CO, USA.
出版信息
Synth Biol (Oxf). 2023 Apr 15;8(1):ysad008. doi: 10.1093/synbio/ysad008. eCollection 2023.
Abstract
摘要
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本文引用的文献
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Engineered live bacteria suppress Pseudomonas aeruginosa infection in mouse lung and dissolve endotracheal-tube biofilms.工程化活菌可抑制小鼠肺部铜绿假单胞菌感染并溶解气管内导管生物膜。
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Development of synthetic biotics as treatment for human diseases.合成生物制剂作为人类疾病治疗手段的研发。
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Engineering living therapeutics with synthetic biology.用合成生物学设计活体治疗药物。
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Antimicrobial resistance: the good, the bad, and the ugly.抗菌药物耐药性：益处、弊端与危害
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Design and Assessment of Anti-Biofilm Peptides: Steps Toward Clinical Application.抗生物膜肽的设计与评估：迈向临床应用的步骤。
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O serotype-independent susceptibility of Pseudomonas aeruginosa to lectin-like pyocins.铜绿假单胞菌对凝集素样绿脓菌素的血清型非依赖性敏感性。
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A predicted S-type pyocin shows a bactericidal activity against clinical Pseudomonas aeruginosa isolates through membrane damage.一种预测的 S 型噬菌素通过破坏细胞膜显示出对临床铜绿假单胞菌分离株的杀菌活性。
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