Pines A, Ehrenfeld M, Fisman E Z, Kaplinsky N, Samra Y, Ronnen M, Kellermann J J
Arch Intern Med. 1986 Jul;146(7):1371-3.
Twenty-five patients with psoriatic arthritis were studied by echocardiography in view of the known association of related seronegative arthropathies with aortic-valve lesions. The study group included 15 men and ten women with a mean age of 46.5 +/- 14.6 years. Twenty-two patients suffered from peripheral disease whereas three also had axial involvement. No aortic-valve lesions were found; however, mitral-valve prolapse (MVP) was detected in 14 patients (56%), nine men and five women. The mean age, mean duration of psoriasis, and mean duration of arthritis were similar in patients with and without MVP. HLA tissue typing, which was done in nine patients with MVP, revealed only one patient with HLA-B27. There was no predominance of any of the typical antigens found in psoriasis (HLA-B13, HLA-Cw6). In a control group of 32 psoriatic patients without arthritis, only two (6.4%) suffered from MVP.
鉴于已知相关血清阴性关节病与主动脉瓣病变有关联，对25例银屑病关节炎患者进行了超声心动图检查。研究组包括15名男性和10名女性，平均年龄为46.5±14.6岁。22例患者患有外周疾病，3例同时有轴向受累。未发现主动脉瓣病变；然而，在14例患者（56%）中检测到二尖瓣脱垂（MVP），其中9名男性和5名女性。有MVP和无MVP的患者的平均年龄、银屑病平均病程和关节炎平均病程相似。对9例有MVP的患者进行了HLA组织分型，仅发现1例患者为HLA - B27。在银屑病中发现的任何典型抗原（HLA - B13、HLA - Cw6）均无优势。在32例无关节炎的银屑病患者对照组中，仅有2例（6.4%）患有MVP。
