Tiwari Atul Kumar, Jamshed Nayer, Sahu Ankit Kumar, Kumar Akshay, Aggarwal Praveen, Bhoi Sanjeev, Mathew Roshan, Ekka Meera
Departments of Emergency Medicine, All India Institute of Medical Sciences, New Delhi, India.
J Emerg Trauma Shock. 2023 Jan-Mar;16(1):3-7. doi: 10.4103/jets.jets_99_22. Epub 2023 Mar 24.
Sepsis is the leading cause of mortality, and various scoring systems have been developed for its early identification and treatment. The objective was to test the ability of quick sequential organ failure assessment (qSOFA) score to identify sepsis and predict sepsis-related mortality in the emergency department (ED).
We conducted a prospective study from July 2018 to April 2020. Consecutive patients with age ≥18 years who presented to the ED with a clinical suspicion of infection were included. Sensitivity, specificity, positive predictive value (PPV), negative predictive values (NPV), and odds ratio (OR) for sepsis related mortality on day 7 and 28 were measured.
A total of 1200 patients were recruited; of which 48 patients were excluded and 17 patients were lost to follow-up. 54 (45.4%) of 119 patients with positive qSOFA (qSOFA >2) died at 7 days and 76 (63.9%) died at 28 days. A total of 103 (10.1%) of 1016 patients with negative qSOFA (qSOFA score <2) died at 7 days and 207 (20.4%) died at 28 days. Patients with positive qSOFA score were at higher odds of dying at 7 days (OR: 3.9, 95% confidence interval [CI]: 3.1-5.2, < 0.001) and 28 days (OR: 6.9, 95% CI: 4.6-10.3, < 0.001). The PPV and NPV with positive qSOFA score to predict 7- and 28-day mortality were 45.4%, 89.9% and 63.9%, 79.6%, respectively.
The qSOFA score can be used as a risk stratification tool in a resource-limited setting to identify infected patients at an increased risk of death.
脓毒症是主要的死亡原因，已开发出各种评分系统用于其早期识别和治疗。目的是测试快速序贯器官衰竭评估（qSOFA）评分在急诊科识别脓毒症和预测脓毒症相关死亡率的能力。
我们于2018年7月至2020年4月进行了一项前瞻性研究。纳入年龄≥18岁、因临床怀疑感染而就诊于急诊科的连续患者。测量了第7天和第28天脓毒症相关死亡率的敏感性、特异性、阳性预测值（PPV）、阴性预测值（NPV）和比值比（OR）。
共招募了1200例患者；其中48例患者被排除，17例患者失访。119例qSOFA阳性（qSOFA>2）的患者中，54例（45.4%）在7天时死亡，76例（63.9%）在28天时死亡。1016例qSOFA阴性（qSOFA评分<2）的患者中，共有103例（10.1%）在7天时死亡，207例（
