Organ Transplantation Center, The Affiliated Hospital of Qingdao University, Qingdao, China.
Precision Medicine Center of Oncology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Transpl Int. 2023 Apr 26;36:10808. doi: 10.3389/ti.2023.10808. eCollection 2023.
The objective of this study was to investigate the significance of portal vein reconstruction in segment IV of the liver on early postoperative liver function recovery in split liver transplantation. The clinical data of patients of right trilobe split liver transplantation in our center were analyzed and divided into two groups, including a group without portal vein reconstruction and a group with portal vein reconstruction. Clinical data of alanine aminotransferase (ALT), aspartate transaminase (AST), albumin (ALB), creatinine (Cr), total bilirubin (TB), alkaline phosphatase (ALP), gamma-glutamyl Transferase (GGT), lactic acid (Lac), and international normalized ratio (INR) levels were analyzed. The technique of segment IV portal vein reconstruction is beneficial to the early postoperative recovery of liver function. Statistically, there was no significant effect of portal vein reconstruction in the IV segment of the liver on the recovery of liver function within 1 week after split liver transplantation. There was no significant difference in survival rate between the control group and reconstruction group over the 6 months follow-up period after surgery.
本研究旨在探讨劈离式肝移植中肝 IV 段门静脉重建对术后早期肝功能恢复的意义。分析总结本中心右三叶劈离式肝移植患者的临床资料,将其分为两组,即未行门静脉重建组和行门静脉重建组。对比分析两组患者丙氨酸转氨酶(ALT)、天门冬氨酸转氨酶(AST)、白蛋白(ALB)、肌酐(Cr)、总胆红素(TB)、碱性磷酸酶(ALP)、γ-谷氨酰转肽酶(GGT)、乳酸(Lac)、国际标准化比值(INR)等肝功能指标水平。IV 段门静脉重建技术有利于劈离式肝移植术后早期肝功能的恢复。但术后 1 周内,肝 IV 段门静脉重建对肝功能的恢复并无明显影响。术后 6 个月随访期间,两组患者的生存率差异无统计学意义。