Puzyrev A A, Ivanova V F
Arkh Anat Gistol Embriol. 1986 Apr;90(4):48-54.
Epithelium of the duodenal mucous membrane has been studied in frog, rat and man by means of electron microscopy. Together with typical endocrinocytes, incretory cells of "mixed" type are revealed in the epithelium. They are classified into two types: 1. exo-endocrinic containing in their cytoplasm simultaneously: a) mucous and EC-granules, b) mucous and S-granules, c) granules specific for Paneth's cells and S-granules, d) granules specific for Paneth's cells and L-granules; 2. endocrinocytes with incretory granules of various types: with D and I, with D and EC, with D and L granules. Various ultramicroscopic organization of the "mixed" exo-endocrinic cells is demonstrated. It can be considered as various stages of their differentiation. In cytoplasm of the "mixed" cells of the second type (endocrinic) a constant presence of D-granules is revealed, that is, evidently, characteristic, within the limits of the gastro-entero-pancreatic system, for the cells with two types of the endocrinic granules.
已通过电子显微镜对青蛙、大鼠和人类十二指肠黏膜上皮进行了研究。除了典型的内分泌细胞外，上皮中还发现了“混合”类型的分泌细胞。它们分为两种类型：1. 外分泌 - 内分泌型，其细胞质中同时含有：a）黏液和EC颗粒，b）黏液和S颗粒，c）潘氏细胞特异性颗粒和S颗粒，d）潘氏细胞特异性颗粒和L颗粒；2. 具有各种类型分泌颗粒的内分泌细胞：具有D和I颗粒、具有D和EC颗粒、具有D和L颗粒。展示了“混合”外分泌 - 内分泌细胞的各种超微结构组织。这可被视为它们分化的不同阶段。在第二种类型（内分泌型）的“混合”细胞的细胞质中，发现始终存在D颗粒，显然，在胃肠胰系统范围内，这是具有两种内分泌颗粒的细胞的特征。
