Batalov A A, Belikov E S
Arkh Patol. 1986;48(4):77-82.
An idea about the second disease as a metamorphosis when the phenomenon of one nature is transformed into phenomenon of the second nature is proposed. There are three stages in the development of the second disease: origin, when clinical and morphological features of initial and new nosologic forms coexist; formation-distinct groups of features of a new nosologic form which preserved a link to the first disease; separation of this new nosologic form with its typical clinical and morphological features. The second disease is metamorphosis of the first disease which develops into a new nosologic entity under the influence of exogenous or endogenous factors.
提出了关于第二种疾病是一种变态的观点，即一种性质的现象转变为第二种性质的现象。第二种疾病的发展有三个阶段：起源阶段，此时初始和新病种形式的临床和形态学特征共存；形成阶段——与第一种疾病保持联系的新病种形式的不同特征组；具有典型临床和形态学特征的这种新病种形式的分离。第二种疾病是第一种疾病的变态，在外部或内部因素的影响下发展成为一种新的病种实体。
