直肠癌放射治疗的进展。
Advances in Radiotherapy for Rectal Cancer.
机构信息
Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, 401 N Broadway, Baltimore, MD 21287, USA.
Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, 401 N Broadway, Baltimore, MD 21287, USA.
出版信息
Surg Oncol Clin N Am. 2023 Jul;32(3):461-473. doi: 10.1016/j.soc.2023.02.003. Epub 2023 Apr 4.
The current preferred standard of care management for patients with locally advanced rectal cancer is total neoadjuvant therapy, in which all chemotherapy and radiotherapy is delivered before surgery. Within this approach, developed in response to persistently high distant failure rates despite excellent local control with preoperative chemoradiotherapy, there remains questions regarding the optimal radiotherapy regimen (short course vs long course) and sequencing of chemotherapy (induction vs consolidation).
目前，局部晚期直肠癌患者的首选护理管理标准是新辅助放化疗，即所有化疗和放疗均在手术前进行。尽管术前放化疗可实现优异的局部控制，但远处失败率仍然居高不下，因此人们针对这种情况开发了这种方法，其中仍然存在关于最佳放疗方案（短程放疗与长程放疗）和化疗序贯（诱导化疗与巩固化疗）的问题。
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