Child Development Service, Children's Health Queensland, Brisbane, Australia.
Department of Respiratory and Sleep Medicine, Queensland Children's Hospital, Brisbane, Australia.
J Clin Sleep Med. 2023 Sep 1;19(9):1625-1631. doi: 10.5664/jcsm.10626.
Diagnostic polysomnography (PSG) is the gold standard test to evaluate sleep-disordered breathing in children. Little is known about how children with neurodevelopmental disorders (NDD) tolerate electrodes and sensors in PSG compared to neurotypical children.
In this retrospective cohort study of children > 12 months of age who underwent diagnostic PSG at our center from 01/01/2021-30/06/2021, we used sleep technician and physician reports to determine how PSG was tolerated in children with NDD compared to neurotypical children. Subanalyses included tolerance of individual electrodes and sensors and subgroups of NDD (eg, Trisomy 21).
A total of 132 children with a NDD and 139 neurotypical children underwent diagnostic PSG. The median age of all children was 8 years, 39% were female, and 50% had a sleep disorder identified on PSG, with no significant differences between NDD and neurotypical groups. The most poorly tolerated sensors for all children were the nasal prongs (poorly tolerated in 30% of all children), followed by thermistor (14%) and electroencephalography electrodes (6%). Children with NDD were > 3 times more likely (odds ratio 3.1, 95% confidence interval 1.8-5.3) to experience problems tolerating any study leads than neurotypical children. Subgroup analysis revealed children with Trisomy 21 had the greatest difficulty tolerating PSG set-up and leads.
This retrospective study demonstrates that children with neurodevelopmental disorders are less likely to tolerate PSG monitoring than neurotypical children and highlights the need to develop alternative measures for evaluation of sleep disorders in this population.
Lanzlinger D, Kevat A, Collaro A, Poh SH, Pérez WP, Chawla J. Tolerance of polysomnography in children with neurodevelopmental disorders compared to neurotypical peers. . 2023;19(9):1625-1631.
诊断性多导睡眠图（PSG）是评估儿童睡眠呼吸障碍的金标准测试。对于神经发育障碍（NDD）儿童与神经典型儿童相比，如何耐受 PSG 中的电极和传感器，人们知之甚少。
在这项对 2021 年 1 月 1 日至 2021 年 6 月 30 日期间在本中心接受诊断性 PSG 的年龄大于 12 个月的儿童的回顾性队列研究中，我们使用睡眠技术员和医生的报告来确定与神经典型儿童相比，NDD 儿童的 PSG 耐受情况。亚分析包括对各个电极和传感器的耐受情况以及 NDD 的亚组（例如，21 三体）。
共有 132 名 NDD 儿童和 139 名神经典型儿童接受了诊断性 PSG。所有儿童的中位年龄为 8 岁，39%为女性，50%在 PSG 上发现睡眠障碍，NDD 和神经典型组之间无显著差异。所有儿童中最难以耐受的传感器是鼻插管（所有儿童中有 30%耐受性差），其次是热敏电阻（14%）和脑电图电极（6%）。与神经典型儿童相比，NDD 儿童（优势比 3.1，95%置信区间 1.8-5.3）体验任何研究导联问题的可能性高出 3 倍以上。亚组分析显示，21 三体的儿童在 PSG 装置和导联的耐受方面有最大的困难。
这项回顾性研究表明，与神经典型儿童相比，神经发育障碍儿童更难以耐受 PSG 监测，并强调需要为该人群开发替代评估睡眠障碍的方法。
Lanzlinger D, Kevat A, Collaro A, Poh SH, Pérez WP, Chawla J. 与神经典型同龄人相比，神经发育障碍儿童对多导睡眠图的耐受性. 2023;19(9):1625-1631.
