Division of Kinesiology, School of Health and Human Performance, Faculty of Health, Dalhousie University, Halifax, NS, Canada.
School of Physiotherapy (Faculty of Health) & Department of Medicine (Faculty of Medicine), Dalhousie University, Halifax, NS, Canada.
J Hum Hypertens. 2023 Nov;37(11):1015-1020. doi: 10.1038/s41371-023-00832-y. Epub 2023 Apr 25.
Whole-day movement guidelines for improving health, recommend that adults engage in at least 150 min week of moderate-to-vigorous aerobic physical activity and limit their sedentary time. In young adults, higher systolic blood pressure variability (BPV) is a precursor for the development of hypertension. The impact of habitual activity that comprises (inter)national guidelines on BPV is unclear. We tested the hypothesis that less habitual physical activity and greater sedentary time would be associated with larger BPV. Ninety-two normotensive participants [age: 19-38 years, body mass index (BMI): 23.6 ± 3.3 kg/m, 44♀] wore an activPAL monitor on their thigh for 7.0 ± 0.3 days. Ten minutes of supine systolic arterial pressure was measured via finger photoplethysmography (115 ± 11 mmHg). Beat-by-beat systolic BPV was measured using the average real variability index (1.1 ± 0.6 mmHg). Relationships between habitual activity outcomes and BPV were assessed via multiple regressions adjusted for age, sex, and BMI. Moderate-intensity physical activity (average: 36 ± 19 min day; β = -0.010, p = 0.02) and time spent in sedentary bouts >1-h (245 ± 134 min day; β = 0.002, p < 0.001), but not light-intensity activity, vigorous-intensity activity, standing time, sedentary breaks, or time spent in sedentary bouts <1-h (all, p > 0.10) were predictors of systolic BPV. Higher moderate physical activity and lower prolonged sedentary time were associated with attenuated systolic BPV responses in young adults. These findings highlight the cardiovascular benefits of habitual activity among younger adults and suggest that simple strategies such as reducing long periods of uninterrupted sitting and increasing moderate-intensity physical activity may be efficacious for reducing the risk of developing or delaying the onset of hypertension.
全天运动指南可改善健康，建议成年人每周至少进行 150 分钟中等至剧烈强度的有氧运动，并限制久坐时间。在年轻人中，较高的收缩压变异性（BPV）是高血压发展的前兆。习惯活动（包括）国际指南对 BPV 的影响尚不清楚。我们检验了以下假设，即习惯性体力活动较少和久坐时间较长与较大的 BPV 相关。92 名血压正常的参与者[年龄：19-38 岁，体重指数（BMI）：23.6±3.3kg/m，44♀]大腿上佩戴 activPAL 监测器 7.0±0.3 天。通过手指光体积描记法测量 10 分钟的仰卧位收缩动脉压（115±11mmHg）。使用平均真实变异性指数（1.1±0.6mmHg）测量逐搏收缩压变异性。通过调整年龄、性别和 BMI 的多元回归评估习惯性活动结果与 BPV 之间的关系。中等强度体力活动（平均：36±19 分钟/天；β=-0.010，p=0.02）和 1 小时以上的久坐时间（245±134 分钟/天；β=0.002，p<0.001），但不是低强度活动、高强度活动、站立时间、久坐休息或 1 小时以下的久坐时间（均，p>0.10）是收缩压 BPV 的预测因子。较高的中等强度体力活动和较低的长时间久坐与年轻人收缩压 BPV 反应减弱相关。这些发现强调了年轻成年人习惯性活动的心血管益处，并表明减少长时间不间断坐姿和增加中等强度体力活动等简单策略可能有助于降低患高血压或延迟高血压发病的风险。
