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久坐后起身活动对心血管参数的影响:系统评价。

Effects of Breaking Up Prolonged Sitting on Cardiovascular Parameters: A systematic Review.

机构信息

Post-graduate Program in Rehabilitation Sciences, Universidade Nove de Julho, Sao Paulo, Brazil.

Instituto Israelita de Ensino e Pesquisa, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

出版信息

Int J Sports Med. 2022 Feb;43(2):97-106. doi: 10.1055/a-1502-6787. Epub 2021 Sep 17.

DOI:10.1055/a-1502-6787
PMID:34535019
Abstract

The aim of this systematic review was to analyze the acute and chronic effects of sitting breaks on cardiovascular parameters. PubMed and Web of Science databases were searched by two independent researchers for relevant studies published until February 2020. Acute or chronic studies reporting the effects of sitting breaks or reduction in sitting time on cardiovascular parameters were examined. The eligibility criteria followed PICOS: Population - Humans ≥ 18 years old; Interventions - Sitting break strategies; Comparisons - Uninterrupted sitting; Outcomes - Cardiovascular parameters (blood pressure, heart rate, ambulatory blood pressure, vascular function, pulse-wave velocity, cerebral blood flow and biomarkers); Study design - Randomized controlled trials, non-randomized non-controlled trials and randomized crossover trials. Forty-five studies were included, where 35 investigated the acute and 10 the chronic effects of sitting breaks or reductions in sitting time. Walking was the main acute study strategy, used in different volumes (1 min 30 s to 30 min), intensities (light to vigorous) and frequencies (every 20 min to every 2 h). Acute studies found improvements on cardiovascular parameters, especially blood pressure, flow-mediated dilation, and biomarkers, whereas chronic studies found improvements mostly on blood pressure. Breaking up or reducing sitting time improves cardiovascular parameters, especially with walking.

摘要

本系统评价的目的是分析坐姿休息对心血管参数的急性和慢性影响。两位独立研究人员检索了 PubMed 和 Web of Science 数据库,以查找截至 2020 年 2 月发表的相关研究。检查了报告坐姿休息或减少坐姿时间对心血管参数影响的急性或慢性研究。纳入标准遵循 PICOS:人群 - 18 岁及以上的人类;干预 - 坐姿休息策略;比较 - 不间断坐姿;结局 - 心血管参数(血压、心率、动态血压、血管功能、脉搏波速度、脑血流和生物标志物);研究设计 - 随机对照试验、非随机非对照试验和随机交叉试验。共纳入 45 项研究,其中 35 项研究调查了坐姿休息或减少坐姿时间的急性影响,10 项研究调查了慢性影响。行走是主要的急性研究策略,采用不同的时长(1 分 30 秒至 30 分钟)、强度(轻度至剧烈)和频率(每 20 分钟至每 2 小时)。急性研究发现,心血管参数,尤其是血压、血流介导的扩张和生物标志物得到了改善,而慢性研究则发现血压得到了改善。打破或减少坐姿时间可改善心血管参数,尤其是通过行走。

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