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宫内节育器导致完全性膀胱穿孔:全国监测系统的病例系列报告。

Complete perforated bladder from intrauterine devices: A case series report from a nationwide monitoring system.

机构信息

Contraceptives Adverse Reaction Surveillance Center of National Health Commission, Nanjing, China.

Jiangsu Health Development Research Center, Nanjing, China.

出版信息

J Obstet Gynaecol Res. 2023 Jul;49(7):1821-1826. doi: 10.1111/jog.15661. Epub 2023 Apr 25.

Abstract

AIM

Complete perforation of the bladder caused by an intrauterine device (IUD) is rare. This study examined the characteristics of patients associated with IUD-related bladder perforation and evaluated the relationship between mislocated IUDs and their potential complications.

METHODS

From October 2005 to December 2021, 13 reports regarding complete perforations to the bladder by IUDs were retrieved from the National Contraceptives Adverse Reaction Monitoring System of China. The clinical features of these cases were analyzed.

RESULTS

The median patient age was 30 (range, 27-46) years. There were four cases (4/13, 30.8%) with IUDs placed during lactation, one case (1/13, 7.7%) with an IUD placed after medical abortion, and eight cases (8/13, 61.5%) placed after menstruation. Seven cases (7/13, 53.9%) were first-time IUD users. The median duration of IUD placement was 47 (range, 1-145) months. Unexpected pregnancy was reported in five cases (5/13, 38.5%). Six cases (6/13, 46.2%) reported bladder stones with varying degrees of abdominal pain or urinary tract infection. Removal methods included laparotomy (four cases), cystoscopy (four cases), laparoscopy (two cases), laparoscopy combined with cystoscopy (two cases), and laparotomy after cystoscopy (one case). All IUDs were successfully removed.

CONCLUSIONS

Complete perforation to the bladder by IUDs is a rare adverse event. Regular follow-up is required after the placement of IUDs. The possibility of uterine perforation should be investigated if IUD users encounter persistent lower abdominal pain or urinary tract infection.

摘要

目的

宫内节育器(IUD)导致的膀胱完全穿孔较为罕见。本研究分析了与 IUD 相关的膀胱穿孔患者的特征,并评估了定位不当的 IUD 与其潜在并发症之间的关系。

方法

2005 年 10 月至 2021 年 12 月,从中国国家节育器不良反应监测系统中检索到 13 例 IUD 完全穿透膀胱的报告。分析这些病例的临床特征。

结果

患者年龄中位数为 30 岁(范围,27-46 岁)。有 4 例(4/13,30.8%)患者在哺乳期放置 IUD,1 例(1/13,7.7%)患者在药物流产后放置 IUD,8 例(8/13,61.5%)患者在月经后放置 IUD。7 例(7/13,53.9%)为首次使用 IUD 者。IUD 放置的中位时间为 47 个月(范围,1-145 个月)。5 例(5/13,38.5%)患者报告意外妊娠。6 例(6/13,46.2%)患者报告有不同程度的膀胱结石并伴有腹痛或尿路感染。取出方法包括剖腹手术(4 例)、膀胱镜检查(4 例)、腹腔镜检查(2 例)、腹腔镜联合膀胱镜检查(2 例)、膀胱镜检查后剖腹手术(1 例)。所有 IUD 均成功取出。

结论

IUD 导致的膀胱完全穿孔是一种罕见的不良事件。放置 IUD 后需要定期随访。如果 IUD 使用者出现持续性下腹痛或尿路感染,应调查是否发生子宫穿孔。

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