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慢型热不稳定同种白蛋白:一种新的变体?

Thermolabile alloalbumin of slow type: a new variant?

作者信息

Montanelli A, Manti F, Airò P, Semprini A E, Airò R

出版信息

Boll Ist Sieroter Milan. 1986;65(1):73-7.

PMID:3718683
Abstract

A new variant of Alloalbumin, with electrophoretic mobility identical to CISMEL standard SO/BS, characterized by thermolability at 56 degrees C of its slow migration band is described in this paper. This thermolabile Alloalbumin was present in 5 out of 10 family members of the original propositus. The new Alloalbumin has been indicated BS/BG according to the CISMEL recommendations. Our observations indicates that Alloalbumins with the same electrophoretic mobility may differ in structural composition as evidentiated by the different behaviour of these Alloalbumins with respect to their thermostability.

摘要

本文描述了一种新的别白蛋白变体,其电泳迁移率与CISMEL标准SO/BS相同,其特征在于其慢迁移带在56摄氏度时具有热不稳定性。这种热不稳定的别白蛋白存在于原主诉患者的10名家族成员中的5名体内。根据CISMEL的建议,这种新的别白蛋白已被命名为BS/BG。我们的观察表明,具有相同电泳迁移率的别白蛋白在结构组成上可能存在差异,这些别白蛋白在热稳定性方面的不同表现就证明了这一点。

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