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罕见肉瘤样上尿路尿路上皮癌变异型的完全缓解:病例报告及文献综述

Complete Response of Rare Sarcomatoid Upper Tract Urothelial Carcinoma Variant: Case Report and Literature Review.

作者信息

Warli Syah Mirsya, Laksmi Lidya Imelda, Lubis Nova Sabrina, Wijaya William Saputra

机构信息

Division of Urology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara - Haji Adam Malik General Hospital, Medan, Indonesia.

Department of Urology, Universitas Sumatera Utara Hospital, Universitas Sumatera Utara, Medan, Indonesia.

出版信息

Case Rep Oncol. 2023 May 12;16(1):325-330. doi: 10.1159/000530264. eCollection 2023 Jan-Dec.

Abstract

Infiltrating urothelial carcinoma sarcomatoid variant is a rare variant of urothelial carcinoma. We report a case of a 68-year-old female with a history of hematuria. CT scan with contrast showed a mass in the 1/3 distal of the right ureter. The biopsy result showed a high-grade infiltrating urothelial carcinoma. A radical nephroureterectomy was performed but at the follow-up after 3 months, there was a recurrent mass and gemcitabine-cisplatin chemotherapy was given. Since a high-grade infiltrating urothelial carcinoma sarcomatoid variant was an aggressive tumor, we need to give more attention to evaluating this tumor.

摘要

浸润性尿路上皮癌肉瘤样变体是尿路上皮癌的一种罕见变体。我们报告一例68岁有血尿病史的女性病例。增强CT扫描显示右输尿管远端1/3处有一肿块。活检结果显示为高级别浸润性尿路上皮癌。行根治性肾输尿管切除术,但术后3个月随访时出现复发性肿块,遂给予吉西他滨-顺铂化疗。由于高级别浸润性尿路上皮癌肉瘤样变体是一种侵袭性肿瘤,我们需要更加重视对该肿瘤的评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08f5/10176196/a5eb2037b19a/cro-2023-0016-0001-530264_F01.jpg

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