Calderon-Martinez Evelyn, Landazuri-Navas Samanta, Vilchez Esmeralda, Cantu-Hernandez Raul, Mosquera-Moscoso Johanna, Encalada Sebastian, Al Lami Zahraa, Zevallos-Delgado Christian, Cinicola John
Department of Internal Medicine, UPMC Harrisburg, Harrisburg, PA, USA.
Department of Internal Medicine, University of the Americas, Quito, Ecuador.
J Clin Med Res. 2023 Apr;15(4):200-207. doi: 10.14740/jocmr4902. Epub 2023 Apr 28.
Hepatocellular carcinoma (HCC) is a common cancer and ranks sixth among all malignancies worldwide. Risk factors for HCC can be classified as infectious or behavioral. Viral hepatitis and alcohol abuse are currently the most common risk factors for HCC; however, nonalcoholic liver disease is expected to become the most common cause of HCC in upcoming years. HCC survival rates vary according to the causative risk factors. As in any malignancy, staging is crucial in making therapeutic decisions. The selection of a specific score should be individualized according to patient characteristics. In this review, we summarize the current data on epidemiology, risk factors, prognostic scores, and survival in HCC.
肝细胞癌(HCC)是一种常见癌症,在全球所有恶性肿瘤中排名第六。HCC的危险因素可分为感染性或行为性。病毒性肝炎和酗酒是目前HCC最常见的危险因素;然而,预计非酒精性肝病在未来几年将成为HCC最常见的病因。HCC的生存率因致病危险因素而异。与任何恶性肿瘤一样,分期对于做出治疗决策至关重要。应根据患者特征个体化选择特定的评分系统。在本综述中,我们总结了目前关于HCC的流行病学、危险因素、预后评分和生存率的数据。