Rosca Ciprian Ilie, Branea Horia Silviu, Sharma Abhinav, Nicoras Violeta Ariana, Borza Claudia, Lighezan Daniel Florin, Morariu Stelian I, Kundnani Nilima Rajpal
Center of Advanced Research in Cardiovascular Pathology and Haemostasis, Department of Internal Medicine I-Medical Semiotics I, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Department of Internal Medicine I-Medical Semiotics II, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Biomedicines. 2023 Apr 11;11(4):1146. doi: 10.3390/biomedicines11041146.
Current data indicate the existence of post-acute COVID-19 syndrome frequently expressing as cardiovascular and respiratory health issues. The long-term evolution of these complications is not yet fully known or predictable. Among the most common clinical manifestations of post-acute COVID-19 syndrome are dyspnea, palpitations, and fatigue, in most cases being transient and without underlying any morphological or functional changes. A single-center retrospective observational study was performed on cases that had presented with new-onset cardiac symptoms post-COVID-19 infection. Records of three male patients without pre-existing chronic cardiovascular pathology who had presented for dyspnea, fatigue, and palpitations around four weeks post-COVID-19 acute phase were studied in detail. The three post-COVID-19 cases exhibited arrhythmic complications after completely healing from the acute phase of the infection. Palpitations, along with chest pain, and possible aggravation or appearance of dyspnea, with syncopal episodes, were found to be present. All the three cases were non-vaccinated against COVID-19 infection. Isolated case reports showing arrhythmic complications such as atrial fibrillation and ventricular tachycardia on a small number of patients with these complications indicate the need for arrhythmic evaluation of large groups of patients in the post-acute stage of the COVID-19 syndrome for a better understanding of the phenomenon and implicitly better care of these patients. It would also be useful to evaluate large groups of patients divided into vaccinated/non-vaccinated against COVID-19 categories to determine whether vaccination per se can provide protection in the occurrence of these types of complications.
当前数据表明，新冠后急性综合征的存在常表现为心血管和呼吸系统健康问题。这些并发症的长期演变尚未完全明确或可预测。新冠后急性综合征最常见的临床表现包括呼吸困难、心悸和疲劳，大多数情况下这些症状是短暂的，且不存在任何形态学或功能改变。对新冠感染后出现新发心脏症状的病例进行了一项单中心回顾性观察研究。详细研究了3例无既往慢性心血管疾病史的男性患者的记录，他们在新冠急性期后约四周出现呼吸困难、疲劳和心悸。这3例新冠后病例在感染急性期完全康复后出现了心律失常并发症。发现存在心悸、胸痛，以及呼吸困难可能加重或出现，并伴有晕厥发作。所有3例患者均未接种新冠疫苗。少数有这些并发症的患者出现房颤和室性心动过速等心律失常并发症的孤立病例报告表明，有必要对新冠综合征急性期后的大量患者进行心律失常评估，以便更好地了解这一现象，并进而更好地护理这些患者。对分为接种/未接种新冠疫苗类别的大量患者进行评估，以确定接种疫苗本身是否能在这些类型并发症的发生中提供保护，这也将是有用的。
