小细胞肺癌的挽救性手术——文献综述
Salvage Surgery for Small-Cell Lung Cancer-A Literature Review.
作者信息
Motas Natalia, Manolache Veronica, Scarci Marco, Nimigean Victor, Nimigean Vanda Roxana, Simion Laurentiu, Mizea Madalina Cristiana, Trifanescu Oana Gabriela, Galateanu Bianca, Gherghe Mirela, Capsa Cristina Mirela, Gonzalez-Rivas Diego, Davidescu Mihnea Dan
机构信息
Discipline of Thoracic Surgery, "Carol Davila" University of Medicine and Pharmacy, 022328 Bucharest, Romania.
Department of Thoracic Surgery, "Prof. Dr. Al. Trestioreanu" Institute of Oncology, 022328 Bucharest, Romania.
出版信息
Cancers (Basel). 2023 Apr 11;15(8):2241. doi: 10.3390/cancers15082241.
(1) Background: Salvation surgery for small-cell lung cancer (SCLC) is exceptionally performed, and only a few cases are published. (2) Methods: There are 6 publications that present 17 cases of salvation surgery for SCLC-the salvation surgery was performed in the context of modern clearly established protocols for SCLC and after including SCLC in the TNM (tumor, node, metastasis) staging in 2010. (3) Results: After a median follow-up of 29 months, the estimated overall survival (OS) was 86 months. The median estimated 2-year survival was 92%, and the median estimated 5-year survival was 66%. (4) Conclusion: Salvage surgery for SCLC is a relatively new and extremely uncommon concept and represents an alternative to second-line chemotherapy. It is valuable because it may offer a reasonable treatment for selected patients, good local control, and a favorable survival outcome.
(1) 背景：小细胞肺癌（SCLC）的挽救性手术极少施行，仅有少数病例被报道。(2) 方法：有6篇文献报道了17例SCLC的挽救性手术——该挽救性手术是在现代明确确立的SCLC治疗方案背景下进行的，且自2010年SCLC被纳入TNM（肿瘤、淋巴结、转移）分期之后。(
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