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三尖瓣修复与置换的 5 年结果:倾向评分匹配分析。

Five-year outcomes of tricuspid valve repair versus replacement; a propensity score-matched analysis.

机构信息

Adult Cardiac Surgery Department, Prince Sultan Cardiac Center, Riyadh, Saudi Arabia.

Cardiac Surgery Department, King Fahd Medical City, Riyadh, Saudi Arabia.

出版信息

Asian Cardiovasc Thorac Ann. 2023 Jun;31(5):413-420. doi: 10.1177/02184923231176508. Epub 2023 May 16.

Abstract

BACKGROUND

Tricuspid valve repair (TVr) is the recommended approach for managing tricuspid regurgitation; however, there is a concern about the long-term durability of the repair. Therefore, this study aimed to compare the long-term outcomes of TVr versus tricuspid valve replacement (TVR) in a matched cohort of patients.

METHODS

This study included 1161 patients who underwent tricuspid valve (TV) surgery from 2009 to 2020. Patients were grouped according to the procedure into two groups: patients who underwent TVr ( = 1020) and patients who underwent TVR (n = 159). The propensity score identified 135 matched pairs.

RESULTS

Renal replacement therapy and bleeding were significantly higher in the TVR group compared to the TVr group both before and after matching. Thirty-day mortality occurred in 38 (3.79%) patients in TVr group versus 3 (1.89%) in the TVR group ( ≤ 0.001) but was not significant after matching. After matching, TV reintervention (hazard ratio (HR): 21.44 (95% CI: 2.17-211.95);   =  0.009) and heart failure rehospitalization (HR: 1.89 (95% CI: 1.13-3.16);   =  0.015) were significantly higher in the TVR group. There was no difference in mortality in the matched cohort (HR: 1.63 (95% CI: 0.72-3.70);   =  0.25).

CONCLUSIONS

TVr was associated with lower renal impairment, reintervention, and heart failure rehospitalization than replacement. TVr remains the preferred approach whenever feasible.

摘要

背景

三尖瓣修复(TVr)是治疗三尖瓣反流的推荐方法;然而,人们对修复的长期耐久性存在担忧。因此,本研究旨在比较 TVr 与三尖瓣置换(TVR)在匹配患者队列中的长期结果。

方法

本研究纳入了 2009 年至 2020 年期间接受三尖瓣(TV)手术的 1161 名患者。根据手术方式将患者分为两组:TVr 组(n=1020)和 TVR 组(n=159)。倾向评分确定了 135 对匹配。

结果

在匹配前后,TVR 组的肾脏替代治疗和出血明显高于 TVr 组。TVr 组有 38 例(3.79%)患者在 30 天内死亡,而 TVR 组有 3 例(1.89%)死亡(≤0.001),但匹配后无统计学意义。匹配后,TV 再次干预(风险比(HR):21.44(95%CI:2.17-211.95);P=0.009)和心力衰竭再入院(HR:1.89(95%CI:1.13-3.16);P=0.015)在 TVR 组中明显更高。在匹配队列中,死亡率无差异(HR:1.63(95%CI:0.72-3.70);P=0.25)。

结论

与置换相比,TVr 与较低的肾功能损害、再次干预和心力衰竭再入院相关。只要可行,TVr 仍然是首选方法。

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