Furtado Cleofina, Zeitoun Rania, Remedios Ian Dos, Wilkes Jonathan, Sumathi Vaiyapuri, Tony George
Department of Diagnostic and Interventional Radiology, University Hospitals of North Midlands NHS Trust, Stoke on Trent, ST4 6QG, United Kingdom.
Department of Diagnostic and Interventional Radiology, Kasr Al-Ainy Faculty of Medicine, Cairo University, Cairo Governorate 4240310, Egypt.
J Orthop Case Rep. 2023 Apr;13(4):30-36. doi: 10.13107/jocr.2023.v13.i04.3604.
Chondrosarcoma of the synovium is a rare and malignant form of cartilaginous tumor that originates in synovial tissue. There have only been a limited number of reported cases of malignant transformation of synovial chondromatosis (SC) into secondary chondrosarcoma (SCH), primarily in the hip and knee, in patients with resistant illness. The occurrence of chondrosarcoma in SC of the wrist is highly uncommon, as evidenced by only a single previous case study that has been documented in the literature.
This study presents a case series of two patients with primary SC who developed SCH at the wrist joint.
Clinicians treating localized swellings of the hand and wrist should be alert to the likelihood of a sarcoma diagnosis to minimize delays to definitive therapy.
滑膜软骨肉瘤是一种起源于滑膜组织的罕见恶性软骨肿瘤。滑膜软骨瘤病(SC)恶变为继发性软骨肉瘤(SCH)的病例报告数量有限,主要发生在髋部和膝部的耐药患者中。腕部SC中发生软骨肉瘤的情况极为罕见,文献中仅记载过一例先前的病例研究。
本研究展示了一组病例,两名原发性SC患者在腕关节处发展为SCH。
治疗手部和腕部局部肿胀的临床医生应警惕肉瘤诊断的可能性,以尽量减少确定性治疗的延迟。