University of Connecticut School of Medicine, Farmington, Connecticut.
Hartford Hospital Department of Pathology and Laboratory Medicine, Hartford, Connecticut.
JBJS Case Connect. 2021 Jul 15;11(3):01709767-202109000-00026. doi: e20.00724.
Synovial chondromatosis (SC) is a rare condition involving the proliferation of cartilage within the synovial membrane secondary to subsynovial connective tissue metaplasia. Malignant transformation to chondrosarcoma is rare. We cite a case of SC of the hip refractory to arthroscopic debridement, found to have secondary chondrosarcoma on aborted total hip arthroplasty, in which curative treatment was ultimately obtained with external hemipelvectomy.
SC has the potential to undergo malignant transformation to chondrosarcoma. The consequences of not recognizing such transformation can significantly impact patient outcomes and limit options for local control surgery and limb salvage.
滑膜软骨瘤病(SC)是一种罕见的疾病,其特征是滑膜下结缔组织化生导致滑膜内软骨增殖。恶性转化为软骨肉瘤较为罕见。我们报告了一例髋关节 SC 患者,经关节镜清理术治疗无效,在髋关节置换术中途发现继发软骨肉瘤,最终通过外半骨盆切除术获得了治愈性治疗。
SC 有恶变为软骨肉瘤的潜力。如果未能认识到这种转化,可能会对患者的预后产生重大影响,并限制局部控制手术和保肢的选择。